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MIRAGE
neuropeptide Y receptor Y1
Summary
- Gene Symbol
-
- NPY1R
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Palmitate
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P25929 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| outflow tract morphogenesis | ||
| glucose metabolic process | ||
| G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | ||
| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | ||
| neuropeptide signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| neuron projection |
| GO Term | Evidence Code | PMID |
|---|---|---|
| peptide YY receptor activity | ||
| pancreatic polypeptide receptor activity | ||
| neuropeptide Y receptor activity | ||
| protein binding | ||
| neuropeptide receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| neuropeptide Y receptor activity |
| neuropeptide binding |
| neuropeptide receptor activity |
| neuropeptide signaling pathway |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
| Neuropeptide Y receptor family |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:2559 | opiate dependence | |
| DOID:670 | amphetamine abuse | |
| DOID:809 | cocaine abuse | |
| DOID:9976 | heroin dependence |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2834 | WB:WBGene00013883 | ||
| 4886 | ZFIN:ZDB-GENE-080221-1 | ||
| 5540 | WB:WBGene00013883 | ||
| 18166 | ZFIN:ZDB-GENE-080221-1 | MOUSE58760 | |
| 18169 | WB:WBGene00020689 | ||
| 19065 | WB:WBGene00013883 | ||
| 29358 | RATNO11171 | ||
| 29471 | WB:WBGene00013883 | ||
| 182921 | ZFIN:ZDB-GENE-080221-1 | ||
| 226278 | WB:WBGene00013883 |
