GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

glutamate decarboxylase 1

Summary

Gene Symbol

GAD1

Organism

Felis catus (domestic cat)

External Links

NCBI Gene

493699

KEGG Gene ID

fca:493699

PubChem

493699

Annotation

Keyword

Decarboxylase
Neurotransmitter biosynthesis
Phosphoprotein
Pyridoxal phosphate
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P14748	67 kDa glutamic acid decarboxylase Glutamate decarboxylase 67 kDa isoform
A0ABI7YT15

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
L-glutamate catabolic process
GABA biosynthetic process	IBA
GABA biosynthetic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-glutamate catabolic process

small molecule catabolic process [inference]

carboxylic acid catabolic process [inference]

dicarboxylic acid catabolic process [inference]

L-glutamate catabolic process

L-amino acid catabolic process [inference]

L-glutamate catabolic process

proteinogenic amino acid catabolic process [inference]

L-glutamate catabolic process

biosynthetic process [inference]

amino acid biosynthetic process [inference]

GABA biosynthetic process

small molecule biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

primary metabolic process [inference]

amino acid metabolic process [inference]

glutamate metabolic process [inference]

L-glutamate catabolic process

amino acid biosynthetic process [inference]

GABA biosynthetic process

amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-glutamate catabolic process

L-amino acid metabolic process [inference]

L-amino acid catabolic process [inference]

L-glutamate catabolic process

proteinogenic amino acid metabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-glutamate catabolic process

non-proteinogenic amino acid metabolic process [inference]

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

small molecule metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

glutamate metabolic process [inference]

L-glutamate catabolic process

dicarboxylic acid catabolic process [inference]

L-glutamate catabolic process

carboxylic acid biosynthetic process [inference]

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

carboxylic acid catabolic process [inference]

dicarboxylic acid catabolic process [inference]

L-glutamate catabolic process

L-amino acid catabolic process [inference]

L-glutamate catabolic process

proteinogenic amino acid catabolic process [inference]

L-glutamate catabolic process

L-amino acid metabolic process [inference]

L-amino acid catabolic process [inference]

L-glutamate catabolic process

proteinogenic amino acid metabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-glutamate catabolic process

non-proteinogenic amino acid metabolic process [inference]

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

small molecule catabolic process [inference]

carboxylic acid catabolic process [inference]

dicarboxylic acid catabolic process [inference]

L-glutamate catabolic process

L-amino acid catabolic process [inference]

L-glutamate catabolic process

proteinogenic amino acid catabolic process [inference]

L-glutamate catabolic process

small molecule biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

non-proteinogenic amino acid biosynthetic process [inference]

GABA biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm	IBA
cytoplasm	IEA
presynaptic active zone	IBA
presynaptic active zone	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
glutamate decarboxylase activity	ISS
glutamate decarboxylase activity	IBA
glutamate decarboxylase activity	IEA
pyridoxal phosphate binding	IEA
identical protein binding	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity [inference]

glutamate decarboxylase activity

binding [inference]

protein binding [inference]

identical protein binding

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01580

Name

glutamate decarboxylase [EC:4.1.1.15]

References

Rhea

H⁺ + L-glutamate

CO₂ + 4-aminobutanoate

Enzyme

4.1.1.15

PMID

About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: [email protected]

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026