GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

ATPase H+/K+ transporting subunit beta

Summary

Gene Symbol

ATP4B

Organism

Homo sapiens (human)

External Links

NCBI Gene

496

KEGG Gene ID

PubChem

496

Alliance of Genome Resources

HGNC:820

Annotation

Keyword

Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Hydrogen ion transport
Potassium transport
Proteomics identification
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P51164	Gastric H(+)/K(+) ATPase subunit beta Proton pump beta chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
potassium ion transport	IEA
sodium ion transport	IEA
intracellular sodium ion homeostasis	IBA
cell adhesion
intracellular potassium ion homeostasis	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

proton transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

regulation of pH [inference]

pH reduction

intracellular monoatomic cation homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to chemical [inference]

response to lipid [inference]

response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

sodium ion transport

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

proton transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

proton transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

biological regulation [inference]

regulation of pH [inference]

pH reduction

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	TAS
plasma membrane	IEA
potassium:proton exchanging ATPase complex
sodium:potassium-exchanging ATPase complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

transporter complex [inference]

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
ATPase activator activity	IBA
protein binding	IPI
P-type potassium:proton transporter activity	TAS
heterocyclic compound binding	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

P-type proton-exporting transporter activity [inference]

P-type potassium:proton transporter activity

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type proton-exporting transporter activity [inference]

P-type potassium:proton transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type potassium:proton transporter activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type potassium:proton transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type proton-exporting transporter activity [inference]

P-type potassium:proton transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type potassium:proton transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type proton-exporting transporter activity [inference]

P-type potassium:proton transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type potassium:proton transporter activity

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type proton-exporting transporter activity [inference]

P-type potassium:proton transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type potassium:proton transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type proton-exporting transporter activity [inference]

P-type potassium:proton transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type potassium:proton transporter activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding

molecular function regulator activity [inference]

molecular function activator activity [inference]

ATPase activator activity

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type proton-exporting transporter activity [inference]

P-type potassium:proton transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type potassium:proton transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type proton-exporting transporter activity [inference]

P-type potassium:proton transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type potassium:proton transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Sodium/potassium-transporting ATPase subunit beta

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ATPase activator activity
intracellular sodium ion homeostasis

Displaying **all 2** entries
InterPro
Sodium/potassium-transporting ATPase subunit beta superfamily
Sodium/potassium-transporting ATPase subunit beta

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:8929	atrophic gastritis	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:0040090	autoimmune gastritis	Alliance of Genome Resources

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	11945	MGI:88114
Rattus norvegicus	24217	RGD:2178
Caenorhabditis elegans	182726	WB:WBGene00007646
Drosophila melanogaster	33953	FB:FBgn0015777
Drosophila melanogaster	33952	FB:FBgn0015776

About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: [email protected]

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026