GlyCosmos Portal

Submissions

furin, paired basic amino acid cleaving enzyme

Summary

Gene Symbol

FURIN

Organism

Homo sapiens (human)

External Links

NCBI Gene

5045

PubChem

5045

Alliance of Genome Resources

HGNC:8568

JoGo

FURIN

TogoVar

FURIN

Annotation

Keyword

3D-structure
Autocatalytic cleavage
Calcium
Cell membrane
Cleavage on pair of basic residues
Disulfide bond
Endosome
Glycoprotein
Golgi apparatus
Heparin-binding
Host-virus interaction
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Secreted
Serine protease
Signal
Transmembrane helix
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
P09958	Dibasic-processing enzyme Paired basic amino acid residue-cleaving enzyme

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 38 in total

1

2

3

4

5

…

Next ›

Last »
GO Term	Evidence Code	PMID
blastocyst formation	IEA
negative regulation of inflammatory response to antigenic stimulus	TAS
obsolete signal peptide processing
proteolysis	IEA
transforming growth factor beta receptor signaling pathway	TAS

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process

catabolic process [inference]

collagen catabolic process

biosynthetic process [inference]

peptide biosynthetic process

collagen metabolic process [inference]

collagen catabolic process

hormone metabolic process [inference]

peptide hormone processing

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

protein maturation

protein processing

signaling receptor ligand precursor processing [inference]

amyloid fibril formation

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

protein maturation

protein processing

signaling receptor ligand precursor processing [inference]

amyloid fibril formation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

extracellular matrix disassembly

extracellular structure organization [inference]

extracellular matrix organization

extracellular matrix disassembly

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling

external encapsulating structure organization [inference]

extracellular matrix organization

extracellular matrix disassembly

supramolecular fiber organization [inference]

amyloid fibril formation

export from cell [inference]

secretion by cell

viral process [inference]

multicellular organismal process [inference]

neurotrophin production [inference]

nerve growth factor production

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

blastocyst formation

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell

export from cell [inference]

secretion by cell

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of inflammatory response to antigenic stimulus

regulation of immune response [inference]

regulation of inflammatory response to antigenic stimulus [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of immune response [inference]

negative regulation of inflammatory response to antigenic stimulus

regulation of signaling [inference]

regulation of signal transduction

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

regulation of sterol transport [inference]

regulation of cholesterol transport

regulation of lipid localization [inference]

regulation of lipid transport [inference]

regulation of sterol transport [inference]

regulation of cholesterol transport

regulation of biological process involved in symbiotic interaction [inference]

modulation by symbiont of entry into host [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of proteolysis [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of immune response [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of neurotrophin production [inference]

negative regulation of nerve growth factor production

regulation of response to stimulus [inference]

regulation of signal transduction

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response [inference]

negative regulation of inflammatory response to antigenic stimulus

regulation of inflammatory response [inference]

regulation of inflammatory response to antigenic stimulus [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of inflammatory response [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of immune response [inference]

negative regulation of inflammatory response to antigenic stimulus

regulation of immune response [inference]

regulation of inflammatory response to antigenic stimulus [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of immune response [inference]

negative regulation of inflammatory response to antigenic stimulus

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response [inference]

negative regulation of inflammatory response to antigenic stimulus

regulation of inflammatory response [inference]

regulation of inflammatory response to antigenic stimulus [inference]

negative regulation of inflammatory response to antigenic stimulus

negative regulation of inflammatory response [inference]

negative regulation of inflammatory response to antigenic stimulus

regulation of viral process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

regulation of viral life cycle [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

regulation of transforming growth factor beta production [inference]

regulation of transforming growth factor beta1 production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

regulation of protein maturation [inference]

regulation of protein processing [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of proteolysis [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein catabolic process

regulation of low-density lipoprotein particle receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of receptor catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

regulation of transforming growth factor beta production [inference]

regulation of transforming growth factor beta1 production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

regulation of protein maturation [inference]

regulation of protein processing [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of proteolysis [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of protein processing [inference]

zymogen inhibition

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein processing [inference]

negative regulation of protein processing [inference]

zymogen inhibition

regulation of protein catabolic process

regulation of low-density lipoprotein particle receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of proteolysis [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

regulation of protein maturation [inference]

regulation of protein processing [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

regulation of receptor catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of protein processing [inference]

zymogen inhibition

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein processing [inference]

negative regulation of protein processing [inference]

zymogen inhibition

regulation of protein catabolic process

regulation of low-density lipoprotein particle receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of proteolysis [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

regulation of protein maturation [inference]

regulation of protein processing [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of proteolysis [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of protein maturation [inference]

negative regulation of protein processing [inference]

zymogen inhibition

negative regulation of receptor catabolic process [inference]

negative regulation of low-density lipoprotein particle receptor catabolic process

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

regulation of transforming growth factor beta production [inference]

regulation of transforming growth factor beta1 production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

regulation of neurotrophin production [inference]

negative regulation of neurotrophin production [inference]

negative regulation of nerve growth factor production

regulation of nerve growth factor production [inference]

negative regulation of nerve growth factor production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of transforming growth factor beta production [inference]

negative regulation of transforming growth factor beta1 production

negative regulation of neurotrophin production [inference]

negative regulation of nerve growth factor production

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing

Displaying entries **1 - 5** of 26 in total

1

2

3

4

5

6

Next ›

Last »
GO Term	Evidence Code	PMID
Golgi membrane	TAS
Golgi membrane	IMP
Golgi membrane	IBA
extracellular region	TAS
extracellular region	IDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

membrane microdomain [inference]

membrane raft

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

Golgi lumen

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

secretory vesicle [inference]

exocytic vesicle

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

secretory vesicle [inference]

exocytic vesicle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

secretory vesicle [inference]

exocytic vesicle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 23 in total

1

2

3

4

5

Next ›

Last »
GO Term	Evidence Code	PMID
protease binding	IPI
endopeptidase activity	TAS
endopeptidase activity	IDA
endopeptidase activity	IMP
serine-type endopeptidase activity	EXP

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity

endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

binding [inference]

protein binding

growth factor binding [inference]

neurotrophin binding [inference]

nerve growth factor binding

enzyme binding [inference]

protease binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

heparan sulfate binding

cation binding [inference]

metal ion binding

organic acid binding [inference]

carboxylic acid binding [inference]

heparan sulfate binding

peptide binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

sulfur compound binding [inference]

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity

serine-type endopeptidase inhibitor activity

enzyme activator activity [inference]

peptidase activator activity [inference]

endopeptidase activator activity

peptidase regulator activity [inference]

peptidase activator activity [inference]

endopeptidase activator activity

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity

serine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity

serine-type endopeptidase inhibitor activity

endopeptidase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

peptidase activator activity [inference]

endopeptidase activator activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity

serine-type endopeptidase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Furin

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
hydrolase activity
peptide hormone processing
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity

Displaying **all 8** entries
InterPro
Galactose-binding-like domain superfamily
Kexin/furin catalytic domain
P domain
Peptidase S8, subtilisin, His-active site
Peptidase S8, subtilisin, Ser-active site
Peptidase S8, subtilisin-related
Peptidase S8/S53 domain superfamily
Peptidase S8/S53 domain

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements