GlyCosmos Portal

Submissions

potassium two pore domain channel subfamily K member 4

Summary

Gene Symbol

KCNK4

Organism

Homo sapiens (human)

External Links

NCBI Gene

50801

KEGG Gene ID

PubChem

50801

Alliance of Genome Resources

HGNC:6279

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell projection
Disease variant
Disulfide bond
Epilepsy
Glycoprotein
Intellectual disability
Metal-binding
Potassium channel
Proteomics identification
Reference proteome
Transmembrane helix
Voltage-gated channel

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q2YDA1	TWIK-related arachidonic acid-stimulated potassium channel protein
Q9NYG8	TWIK-related arachidonic acid-stimulated potassium channel protein Two pore potassium channel KT4.1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

1

2

3

4

5

Next ›

Last »
GO Term	Evidence Code	PMID
potassium ion transport	TAS
memory	IEA
response to mechanical stimulus	IEA
neuronal action potential	ISS
neuronal action potential	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to fatty acid

cellular response to arachidonate

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid

cellular response to arachidonate

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular response to pH [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

cognition [inference]

learning or memory [inference]

memory

behavior [inference]

learning or memory [inference]

memory

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

cellular response to temperature stimulus

response to pH [inference]

response to alkaline pH [inference]

cellular response to alkaline pH

response to acidic pH [inference]

cellular response to acidic pH

cellular response to pH [inference]

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular response to pH [inference]

response to chemical [inference]

response to lipid [inference]

response to fatty acid [inference]

cellular response to fatty acid

cellular response to arachidonate

response to arachidonate [inference]

cellular response to arachidonate

cellular response to lipid [inference]

cellular response to fatty acid

cellular response to arachidonate

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to fatty acid

cellular response to arachidonate

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid

cellular response to arachidonate

response to oxygen-containing compound [inference]

response to fatty acid [inference]

cellular response to fatty acid

cellular response to arachidonate

response to arachidonate [inference]

cellular response to arachidonate

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid

cellular response to arachidonate

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

detection of stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to fatty acid

cellular response to arachidonate

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid

cellular response to arachidonate

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular response to pH [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane potential [inference]

action potential [inference]

neuronal action potential

Displaying entries **6 - 10** of 11 in total

« First

‹ Prev

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
plasma membrane	IEA
membrane	IEA
axon	IEA
node of Ranvier	ISS
node of Ranvier	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex

cellular anatomical structure [inference]

membrane

plasma membrane

node of Ranvier

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying entries **1 - 5** of 15 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
potassium channel activity	TAS
potassium channel activity	IDA
potassium channel activity	IEA
protein binding	IPI
outward rectifier potassium channel activity	IDA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

temperature-gated cation channel activity

mechanosensitive monoatomic cation channel activity [inference]

mechanosensitive potassium channel activity

mechanosensitive monoatomic ion channel activity [inference]

mechanosensitive monoatomic cation channel activity [inference]

mechanosensitive potassium channel activity

temperature-gated ion channel activity [inference]

temperature-gated cation channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

temperature-gated cation channel activity

mechanosensitive monoatomic cation channel activity [inference]

mechanosensitive potassium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

temperature-gated cation channel activity

mechanosensitive monoatomic cation channel activity [inference]

mechanosensitive potassium channel activity

mechanosensitive monoatomic ion channel activity [inference]

mechanosensitive monoatomic cation channel activity [inference]

mechanosensitive potassium channel activity

temperature-gated ion channel activity [inference]

temperature-gated cation channel activity

gated channel activity [inference]

mechanosensitive monoatomic ion channel activity [inference]

mechanosensitive monoatomic cation channel activity [inference]

mechanosensitive potassium channel activity

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

temperature-gated ion channel activity [inference]

temperature-gated cation channel activity

narrow pore channel activity [inference]

leak channel activity [inference]

potassium ion leak channel activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Potassium channel subfamily K member

Functional Category

E: Amino acid transport and metabolism
K: Transcription
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
monoatomic ion transport
outward rectifier potassium channel activity
potassium channel activity
potassium ion leak channel activity
stabilization of membrane potential