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acyl-CoA oxidase 1
Summary
- Gene Symbol
-
- ACOX1
- Aliases
-
- PALMCOX
- palmitoyl-CoA oxidase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Deafness
- Disease variant
- FAD
- Fatty acid metabolism
- Neuropathy
- Oxidoreductase
- Peroxisome
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q15067 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| very long-chain fatty acid metabolic process |
|
|
| very long-chain fatty acid metabolic process |
|
|
| generation of precursor metabolites and energy |
|
|
| lipid metabolic process |
|
|
| fatty acid metabolic process |
|
GO Hierarchy
- generation of precursor metabolites and energy
biological process
cellular process [inference]
metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| peroxisome |
|
|
| peroxisome |
|
|
| peroxisome |
|
|
| peroxisomal membrane |
|
|
| peroxisomal matrix |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| acyl-CoA oxidase activity |
|
|
| acyl-CoA oxidase activity |
|
|
| acyl-CoA oxidase activity |
|
|
| acyl-CoA oxidase activity |
|
|
| fatty acid binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- acyl-Coenzyme A oxidase
- Functional Category
-
- I: Lipid transport and metabolism
- P: Inorganic ion transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050797 | peroxisomal acyl-CoA oxidase deficiency | |
| DOID:0070516 | Mitchell syndrome |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000248 | Brachycephaly |
| HP:0000286 | Epicanthus |
| HP:0000316 | Hypertelorism |
| HP:0000369 | Low-set ears |
| HP:0000407 | Sensorineural hearing impairment |
| HP:0000431 | Wide nasal bridge |
| HP:0000486 | Strabismus |
| HP:0000510 | Rod-cone dystrophy |
| Disease ID | Disease Name |
|---|---|
| OMIM:618960 |
|
| ORPHA:2971 |
|
| OMIM:264470 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002411
- Gene Name
- acyl-CoA oxidase 1, palmitoyl
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 37028 | FB:FBgn0027572 | |
| 852667 | SGD:S000003173 |
