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Repository for lectin-assisted multimodality data
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MIRAGE
profilin 1
Summary
- Gene Symbol
-
- PFN1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Actin-binding
- Amyotrophic lateral sclerosis
- Cytoskeleton
- Direct protein sequencing
- Disease variant
- Isopeptide bond
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P07737 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| neural tube closure |
|
|
| regulation of transcription by RNA polymerase II |
|
|
| positive regulation of epithelial cell migration |
|
|
| actin cytoskeleton organization |
|
|
| actin cytoskeleton organization |
|
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of actin filament-based process [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| adenyl-nucleotide exchange factor activity |
|
|
| phosphotyrosine residue binding |
|
|
| RNA binding |
|
|
| actin binding |
|
|
| actin binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- profilin
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| actin binding |
| actin monomer binding |
| sequestering of actin monomers |
| InterPro |
|---|
| Profilin conserved site |
| Profilin superfamily |
| Profilin, eukaryotic type |
| Profilin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060209 | amyotrophic lateral sclerosis type 18 |
