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acetylcholinesterase (Yt blood group)

Summary

Gene Symbol

ACHE

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 540446
KEGG Gene ID: bta:540446
PubChem: 540446

Annotation

Keyword

Alternative splicing
Cell membrane
Direct protein sequencing
Disulfide bond
GPI-anchor
Neurotransmitter degradation
Reference proteome
Secreted
Serine esterase
Signal
Synapse

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P23795
F1MIM4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
regulation of receptor recycling
osteoblast development	IEA
acetylcholine catabolic process	IBA
acetylcholine catabolic process	IEA
cell adhesion	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

signal transduction [inference]

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway

metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine catabolic process

catabolic process [inference]

acetylcholine catabolic process

choline metabolic process

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

cellular developmental process [inference]

cell development [inference]

osteoblast development

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

osteoblast development

retina development in camera-type eye

cellular developmental process [inference]

cell development [inference]

osteoblast development

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of receptor recycling

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of cellular process [inference]

signal transduction [inference]

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway

regulation of metabolic process [inference]

regulation of macromolecule metabolic process [inference]

regulation of receptor recycling

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
basement membrane	IEA
obsolete extracellular space
Golgi apparatus	IEA
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

cell junction [inference]

synapse

neuromuscular junction

external encapsulating structure [inference]

extracellular matrix [inference]

basement membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
amyloid-beta binding	IDA
acetylcholinesterase activity	IBA
acetylcholinesterase activity	IEA
collagen binding	IEA
serine hydrolase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

cholinesterase activity [inference]

acetylcholinesterase activity

serine hydrolase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

laminin binding

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

acetylcholine binding

peptide binding [inference]

amyloid-beta binding

protein-containing complex binding [inference]

collagen binding

extracellular matrix binding [inference]

laminin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Carboxylesterase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
hydrolase activity

Displaying **all 4** entries
InterPro
Alpha/Beta hydrolase fold
Carboxylesterase type B, active site
Carboxylesterase type B, conserved site
Carboxylesterase, type B

KEGG BRITE Database

Orthology

K01049

Name

acetylcholinesterase [EC:3.1.1.7]

References

Rhea

RHEA:17561

acetylcholine + H₂O

choline + H⁺ + acetate

Enzyme

3.1.1.7

PMID

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements