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Guidelines
MIRAGE
5'-3' exoribonuclease 1
Summary
- Gene Symbol
-
- XRN1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- DNA-binding
- Exonuclease
- Phosphoprotein
- Proteomics identification
- RNA-binding
- Reference proteome
- Tumor suppressor
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8IZH2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
|
|
| deadenylation-dependent decapping of nuclear-transcribed mRNA |
|
|
| nuclear-transcribed mRNA catabolic process |
|
|
| nuclear-transcribed mRNA catabolic process |
|
|
| nuclear-transcribed mRNA catabolic process |
|
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G-quadruplex RNA binding |
|
|
| nucleic acid binding |
|
|
| RNA binding |
|
|
| RNA binding |
|
|
| RNA binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- 5 -3 exoribonuclease 1
- Functional Category
-
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| 5'-3' RNA exonuclease activity |
| 5'-3' exonuclease activity |
| hydrolase activity |
| nuclear-transcribed mRNA catabolic process |
| nuclease activity |
| nucleic acid metabolic process |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease |
