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heparanase 2

Summary

Gene Symbol

Hpse2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

545291

PubChem

545291

Alliance of Genome Resources

MGI:2685814

Annotation

Keyword

Extracellular matrix
Glycoprotein
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
B2RY83

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cell population proliferation	IMP	25510506
positive regulation of cell population proliferation	IMP	25510506
extracellular matrix organization	IMP	25510506
extracellular matrix organization	IBA

GO Hierarchy

biological process

cellular process [inference]

cell population proliferation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	IBA
membrane	IEA
extracellular matrix	ISO
extracellular matrix	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix

Displaying **all 3** entries
GO Term	Evidence Code	PMID
hydrolase activity, acting on glycosyl bonds	IEA
heparan sulfate proteoglycan binding	ISO
heparan sulfate proteoglycan binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds

binding [inference]

protein binding [inference]

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

carbohydrate derivative binding [inference]

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

sulfur compound binding [inference]

heparan sulfate proteoglycan binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Heparanase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
hydrolase activity, acting on glycosyl bonds

Displaying **all 2** entries
InterPro
Glycoside hydrolase superfamily
Glycoside hydrolase, family 79

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050816	urofacial syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 69 in total

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Species	Gene ID	Orthologous MAtrix
Neolamprologus brichardi	102781816	NEOBR04029
Astyanax mexicanus	103034333	ASTMX02798
Poecilia formosa	103152246	POEFO17852
Poecilia reticulata	103476909	POERE09082
Nannospalax galili	103733180	NANGA08365
Rhinopithecus roxellana	104682796	RHIRO10019
Esox lucius	105021381	ESOLU17193
Macaca nemestrina	105478425	MACNE28060
Mandrillus leucophaeus	105554353	MANLE13757
Cercocebus atys	105581816	CERAT19857

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements