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solute carrier family 66 member 1

Summary

Gene Symbol

SLC66A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

54896

KEGG Gene ID

PubChem

54896

Alliance of Genome Resources

HGNC:26001

Annotation

Keyword

Alternative splicing
Amino-acid transport
Glycoprotein
Lysosome
Proteomics identification
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A024RAA1	PQ-loop repeat-containing protein 2 Solute carrier family 66 member 1
Q6ZP29	PQ-loop repeat-containing protein 2 Solute carrier family 66 member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
amino acid transport
lysine transport	IDA
transmembrane transport	TAS
intracellular amino acid homeostasis	IDA
intracellular amino acid homeostasis	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular amino acid homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular amino acid homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

organic cation transport [inference]

L-histidine transmembrane transport

L-lysine transport [inference]

L-arginine transmembrane transport

organic anion transport [inference]

carboxylic acid transport [inference]

aromatic amino acid transport [inference]

L-histidine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

organic acid transport [inference]

carboxylic acid transport [inference]

aromatic amino acid transport [inference]

L-histidine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

transmembrane transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

nitrogen compound transport [inference]

aromatic amino acid transport [inference]

L-histidine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

azole transmembrane transport [inference]

L-histidine transmembrane transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
lysosomal membrane	TAS
lysosomal membrane	IDA
lysosomal membrane	IBA
lysosomal membrane	IEA
organelle membrane	IDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
L-histidine transmembrane transporter activity	IDA
protein binding	IPI
basic amino acid transmembrane transporter activity	ISS
basic amino acid transmembrane transporter activity	TAS
basic amino acid transmembrane transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

azole transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

lysosomal amino acid transporter 1

Functional Category

I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying 1 entry
InterPro
PQ-loop repeat

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	212555	MGI:2384837
Rattus norvegicus	362642	RGD:1311627
Caenorhabditis elegans	3565323	WB:WBGene00021546
Saccharomyces cerevisiae S288C	854061	SGD:S000005452