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nuclear receptor binding SET domain protein 3

Summary

Gene Symbol

NSD3

Organism

Homo sapiens (human)

External Links

NCBI Gene

54904

PubChem

54904

Alliance of Genome Resources

HGNC:12767

JoGo

NSD3

TogoVar

NSD3

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Chromatin regulator
Chromosomal rearrangement
Chromosome
Coiled coil
Isopeptide bond
Methyltransferase
Nucleus
Phosphoprotein
Proteomics identification
Proto-oncogene
Reference proteome
Repeat
S-adenosyl-L-methionine
Transcription regulation
Ubl conjugation
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9BZ95	Nuclear SET domain-containing protein 3 Protein whistle WHSC1-like 1 isoform 9 with methyltransferase activity to lysine Wolf-Hirschhorn syndrome candidate 1-like protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
chromatin remodeling	IEA
regulation of transcription, DNA-templated	IBA
regulation of DNA-templated transcription	IBA
regulation of DNA-templated transcription	IEA
regulation of transcription, DNA-templated	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

methylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin remodeling

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
chromatin	IBA
nucleus	IC
nucleus	IMP
nucleus	IBA
nucleus	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

chromosome

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
zinc ion binding
histone methyltransferase activity	IEA
histone H3K4 methyltransferase activity	IEA
histone H3K36 methyltransferase activity	IMP

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H3K4 methyltransferase activity

histone H3K4 dimethyltransferase activity

histone H3K36 methyltransferase activity

histone H3K27 methyltransferase activity

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H3K4 methyltransferase activity

histone H3K4 dimethyltransferase activity

histone H3K36 methyltransferase activity

histone H3K27 methyltransferase activity

histone methyltransferase activity

histone H3 methyltransferase activity

histone H3K4 methyltransferase activity

histone H3K4 dimethyltransferase activity

histone H3K36 methyltransferase activity

histone H3K27 methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H3K4 methyltransferase activity

histone H3K4 dimethyltransferase activity

histone H3K36 methyltransferase activity

histone H3K27 methyltransferase activity

catalytic activity, acting on a protein [inference]

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H3K4 methyltransferase activity

histone H3K4 dimethyltransferase activity

histone H3K36 methyltransferase activity

histone H3K27 methyltransferase activity

histone methyltransferase activity

histone H3 methyltransferase activity

histone H3K4 methyltransferase activity

histone H3K4 dimethyltransferase activity

histone H3K36 methyltransferase activity

histone H3K27 methyltransferase activity

histone modifying activity [inference]

histone methyltransferase activity

histone H3 methyltransferase activity

histone H3K4 methyltransferase activity

histone H3K4 dimethyltransferase activity

histone H3K36 methyltransferase activity

histone H3K27 methyltransferase activity

binding [inference]

protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

molecular function regulator activity [inference]

molecular function activator activity [inference]

transcription regulator activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Histone-lysine N-methyltransferase

Functional Category

C: Energy production and conversion
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
histone H3 methyltransferase activity
histone methyltransferase activity
metal ion binding
protein-lysine N-methyltransferase activity
transferase activity

Displaying entries **1 - 10** of 11 in total

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InterPro
AWS domain
NSD, Cys-His rich domain
PWWP domain
Post-SET domain
SET domain superfamily
SET domain
Zinc finger, FYVE/PHD-type
Zinc finger, PHD-finger
Zinc finger, PHD-type, conserved site
Zinc finger, PHD-type