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anoctamin 1

Summary

Gene Symbol

ANO1

Organism

Homo sapiens (human)

External Links

NCBI Gene

55107

KEGG Gene ID

[""]

PubChem

55107

Alliance of Genome Resources

HGNC:21625

Annotation

Keyword

Alternative splicing
Calcium
Cell membrane
Cell projection
Chloride channel
Developmental protein
Disease variant
Disulfide bond
Glycoprotein
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Synapse
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9NW72
Q5XXA6	Discovered on gastrointestinal stromal tumors protein 1 Oral cancer overexpressed protein 2 Transmembrane protein 16A Tumor-amplified and overexpressed sequence 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
chloride transport	ISS
chloride transport	IMP
chloride transport	IEA
phospholipase C-activating G protein-coupled receptor signaling pathway	ISS
phospholipase C-activating G protein-coupled receptor signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled receptor signaling pathway

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to peptide

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

glial cell projection elongation

multicellular organismal process [inference]

secretion by tissue [inference]

mucus secretion

developmental process [inference]

anatomical structure morphogenesis [inference]

cell projection morphogenesis [inference]

glial cell projection elongation

anatomical structure development [inference]

animal organ development [inference]

trachea development

response to stimulus [inference]

response to stress [inference]

response to heat [inference]

cellular response to heat

cellular response to stress [inference]

cellular response to heat

response to external stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat [inference]

cellular response to heat

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to peptide

response to peptide [inference]

cellular response to peptide

detection of stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to peptide

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to membrane

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport

monoatomic anion transport [inference]

chloride transport

chloride transmembrane transport

iodide transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport

chloride transmembrane transport

iodide transport

secretion [inference]

body fluid secretion [inference]

mucus secretion

secretion by tissue [inference]

mucus secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled receptor signaling pathway

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion [inference]

mucus secretion

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
nucleoplasm
plasma membrane	ISS
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

cellular anatomical structure [inference]

nucleoplasm

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

synaptic membrane [inference]

presynaptic membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

side of membrane [inference]

external side of plasma membrane

presynapse

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	IEA
calcium-activated cation channel activity	IDA
intracellularly calcium-gated chloride channel activity	ISS
intracellularly calcium-gated chloride channel activity	IDA
intracellularly calcium-gated chloride channel activity	IMP