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MIRAGE
protein kinase C alpha
Summary
- Gene Symbol
-
- PRKCA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Angiogenesis
- Apoptosis
- Calcium
- Cell adhesion
- Cell membrane
- Cytoplasm
- Direct protein sequencing
- Metal-binding
- Mitochondrion
- Nucleus
- Phosphoprotein
- Proteomics identification
- Proto-oncogene
- Reference proteome
- Repeat
- Serine/threonine-protein kinase
- Zinc
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to reactive oxygen species |
|
|
| angiogenesis |
|
|
| positive regulation of endothelial cell proliferation |
|
|
| desmosome assembly |
|
|
| chromatin remodeling |
|
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus |
|
|
| nucleoplasm |
|
|
| cytoplasm |
|
|
| cytoplasm |
|
|
| mitochondrion |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase activity |
|
|
| protein kinase activity |
|
|
| protein serine/threonine kinase activity |
|
|
| protein serine/threonine kinase activity |
|
|
| protein serine/threonine kinase activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- protein kinase C
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| kinase activity |
| metal ion binding |
| nucleotide binding |
| phosphorylation |
| transferase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10286 | prostate carcinoma | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:2394 | ovarian cancer | |
| DOID:3070 | high grade glioma | |
| DOID:3774 | chordoid glioma | |
| DOID:4552 | large cell carcinoma |
