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regulator of chromosome condensation 2

Summary

Gene Symbol

RCC2

Organism

Homo sapiens (human)

External Links

NCBI Gene

55920

PubChem

55920

Alliance of Genome Resources

HGNC:30297

JoGo

RCC2

TogoVar

RCC2

Annotation

Keyword

3D-structure
Acetylation
Cell membrane
Centromere
Chromosome
Cytoskeleton
Guanine-nucleotide releasing factor
Microtubule
Mitosis
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9P258	RCC1-like protein TD-60 Telophase disk protein of 60 kDa
A0A024RAC5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
integrin-mediated signaling pathway	IDA
regulation of fibroblast migration	IEA
positive regulation of G2/M transition of mitotic cell cycle	IMP
regulation of cell migration	ISS
regulation of cell migration	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-substrate junction assembly [inference]

focal adhesion assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-substrate junction assembly [inference]

focal adhesion assembly

cell-substrate junction organization [inference]

cell-substrate junction assembly [inference]

focal adhesion assembly

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region [inference]

protein localization to kinetochore [inference]

chromosome passenger complex localization to kinetochore

protein localization to condensed chromosome [inference]

protein localization to kinetochore [inference]

chromosome passenger complex localization to kinetochore

protein-containing complex localization [inference]

chromosome passenger complex localization to kinetochore

establishment of localization [inference]

establishment of protein localization

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

regulation of fibroblast migration

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of chromosome segregation [inference]

positive regulation of attachment of spindle microtubules to kinetochore

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

negative regulation of biological process [inference]

negative regulation of GTPase activity

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion [inference]

negative regulation of focal adhesion assembly

negative regulation of substrate adhesion-dependent cell spreading

negative regulation of cellular component organization [inference]

negative regulation of cell-substrate junction organization [inference]

negative regulation of focal adhesion assembly

negative regulation of cell junction assembly [inference]

negative regulation of focal adhesion assembly

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion [inference]

negative regulation of focal adhesion assembly

negative regulation of substrate adhesion-dependent cell spreading

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

negative regulation of cell-matrix adhesion [inference]

negative regulation of focal adhesion assembly

regulation of focal adhesion assembly [inference]

negative regulation of focal adhesion assembly

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion [inference]

negative regulation of focal adhesion assembly

negative regulation of substrate adhesion-dependent cell spreading

regulation of substrate adhesion-dependent cell spreading [inference]

negative regulation of substrate adhesion-dependent cell spreading

regulation of cellular component biogenesis [inference]

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of ruffle assembly

regulation of cell junction assembly [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly [inference]

negative regulation of focal adhesion assembly

negative regulation of cell junction assembly [inference]

negative regulation of focal adhesion assembly

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of chromosome segregation [inference]

positive regulation of attachment of spindle microtubules to kinetochore

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion [inference]

negative regulation of focal adhesion assembly

negative regulation of substrate adhesion-dependent cell spreading

negative regulation of cellular component organization [inference]

negative regulation of cell-substrate junction organization [inference]

negative regulation of focal adhesion assembly

negative regulation of cell junction assembly [inference]

negative regulation of focal adhesion assembly

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of ruffle assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of ruffle assembly

negative regulation of cellular component organization [inference]

negative regulation of cell-substrate junction organization [inference]

negative regulation of focal adhesion assembly

negative regulation of cell junction assembly [inference]

negative regulation of focal adhesion assembly

regulation of cell-substrate junction organization [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly [inference]

negative regulation of focal adhesion assembly

negative regulation of cell-substrate junction organization [inference]

negative regulation of focal adhesion assembly

regulation of cell junction assembly [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly [inference]

negative regulation of focal adhesion assembly

negative regulation of cell junction assembly [inference]

negative regulation of focal adhesion assembly

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle process [inference]

regulation of chromosome segregation [inference]

positive regulation of chromosome segregation [inference]

positive regulation of attachment of spindle microtubules to kinetochore

regulation of attachment of spindle microtubules to kinetochore [inference]

positive regulation of attachment of spindle microtubules to kinetochore

positive regulation of cell cycle process [inference]

positive regulation of chromosome segregation [inference]

positive regulation of attachment of spindle microtubules to kinetochore

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of chromosome segregation [inference]

positive regulation of attachment of spindle microtubules to kinetochore

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell motility [inference]

regulation of cell migration

regulation of fibroblast migration

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of GTPase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of GTPase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

negative regulation of GTPase activity

negative regulation of hydrolase activity [inference]

negative regulation of GTPase activity

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
chromosome, centromeric region	IEA
nucleus	IEA
chromosome	IEA
nucleolus	IEA
spindle	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

early endosome membrane

midbody

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

spindle midzone [inference]

mitotic spindle midzone

chromosomal region [inference]

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
RNA binding	HDA
guanyl-nucleotide exchange factor activity
protein binding	IPI
microtubule binding	IMP
protein kinase binding	IPI

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

GTPase binding [inference]

small GTPase binding

protein domain specific binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

guanyl-nucleotide exchange factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

RCC2 protein

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Protein RCC2
Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Regulator of chromosome condensation, RCC1

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements