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Guidelines
MIRAGE
mitogen-activated protein kinase kinase 1
Summary
- Gene Symbol
-
- MAP2K1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Cardiomyopathy
- Coiled coil
- Cytoskeleton
- Direct protein sequencing
- Disease variant
- Ectodermal dysplasia
- Intellectual disability
- Membrane
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Serine/threonine-protein kinase
- Tyrosine-protein kinase
- Proteins
| UniProt | Protein Name |
|---|---|
| A4QPA9 |
|
| A0A8I5KYS7 |
|
| Q02750 |
|
| B4DFY5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| MAPK cascade |
|
|
| MAPK cascade |
|
|
| regulation of vascular associated smooth muscle contraction |
|
|
| chemotaxis |
|
|
| response to oxidative stress |
|
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| MAP kinase scaffold activity |
|
|
| protein binding |
|
|
| protein binding |
|
|
| ATP binding |
|
|
| protein kinase binding |
|
GO Hierarchy
Disease
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 26395 | MGI:1346866 |
