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protein associated with LIN7 1, MAGUK family member

Summary

Gene Symbol

Pals1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56217

PubChem

56217

Alliance of Genome Resources

MGI:1927339

Annotation

Keyword

3D-structure
ATP-binding
Cell membrane
Cell projection
Golgi apparatus
Phosphoprotein
Reference proteome
Repeat
SH3 domain
Tight junction

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9JLB2	MAGUK p55 subfamily member 5 Protein associated with Lin-7 1
B2RRY4	MAGUK p55 subfamily member 5 Protein associated with Lin-7 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
morphogenesis of an epithelial sheet	ISO
morphogenesis of an epithelial sheet	IBA
morphogenesis of an epithelial sheet	IEA
plasma membrane organization	IMP
brain development	IEA

GO Hierarchy

biological process

cellular process [inference]

establishment or maintenance of cell polarity [inference]

establishment or maintenance of polarity of embryonic epithelium

establishment or maintenance of bipolar cell polarity [inference]

establishment or maintenance of apical/basal cell polarity [inference]

establishment or maintenance of epithelial cell apical/basal polarity

ensheathment of neurons [inference]

axon ensheathment [inference]

myelination

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

nucleoside monophosphate metabolic process [inference]

purine nucleoside monophosphate metabolic process [inference]

purine ribonucleoside monophosphate metabolic process [inference]

GMP metabolic process

nucleoside diphosphate metabolic process [inference]

purine nucleoside diphosphate metabolic process [inference]

purine ribonucleoside diphosphate metabolic process [inference]

GDP metabolic process

ribonucleoside diphosphate metabolic process [inference]

purine ribonucleoside diphosphate metabolic process [inference]

GDP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

nucleoside monophosphate metabolic process [inference]

purine nucleoside monophosphate metabolic process [inference]

purine ribonucleoside monophosphate metabolic process [inference]

GMP metabolic process

nucleoside diphosphate metabolic process [inference]

purine nucleoside diphosphate metabolic process [inference]

purine ribonucleoside diphosphate metabolic process [inference]

GDP metabolic process

ribonucleoside diphosphate metabolic process [inference]

purine ribonucleoside diphosphate metabolic process [inference]

GDP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

nucleoside monophosphate metabolic process [inference]

purine nucleoside monophosphate metabolic process [inference]

purine ribonucleoside monophosphate metabolic process [inference]

GMP metabolic process

nucleoside diphosphate metabolic process [inference]

purine nucleoside diphosphate metabolic process [inference]

purine ribonucleoside diphosphate metabolic process [inference]

GDP metabolic process

ribonucleoside diphosphate metabolic process [inference]

purine ribonucleoside diphosphate metabolic process [inference]

GDP metabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

nucleoside monophosphate metabolic process [inference]

purine nucleoside monophosphate metabolic process [inference]

purine ribonucleoside monophosphate metabolic process [inference]

GMP metabolic process

nucleoside diphosphate metabolic process [inference]

purine nucleoside diphosphate metabolic process [inference]

purine ribonucleoside diphosphate metabolic process [inference]

GDP metabolic process

ribonucleoside diphosphate metabolic process [inference]

purine ribonucleoside diphosphate metabolic process [inference]

GDP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis [inference]

generation of neurons

cell development [inference]

neuron development [inference]

central nervous system neuron development

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myelin assembly

membrane organization [inference]

plasma membrane organization

myelin maintenance [inference]

peripheral nervous system myelin maintenance

developmental process [inference]

anatomical structure morphogenesis [inference]

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of an epithelial sheet

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

myelin assembly

anatomical structure development [inference]

cerebral cortex development

cell development [inference]

neuron development [inference]

central nervous system neuron development

animal organ development [inference]

brain development

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis [inference]

generation of neurons

cell development [inference]

neuron development [inference]

central nervous system neuron development

localization [inference]

macromolecule localization [inference]

intracellular protein localization

protein localization to myelin sheath abaxonal region

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of cellular response to transforming growth factor beta stimulus [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

Displaying entries **1 - 5** of 30 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
cytoplasm	IEA
Golgi apparatus	ISS
Golgi apparatus	ISO
Golgi apparatus	IEA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell junction

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

tight junction [inference]

bicellular tight junction

myelin sheath adaxonal region

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

apical part of cell

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
GMP kinase activity	ISS
protein binding	IPI
ATP binding	IEA
protein domain specific binding	ISO
protein domain specific binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

nucleobase-containing compound kinase activity [inference]

nucleoside monophosphate kinase activity [inference]

GMP kinase activity

phosphotransferase activity, phosphate group as acceptor [inference]

nucleoside monophosphate kinase activity [inference]

GMP kinase activity

binding [inference]

protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

MAGUK p55 subfamily member

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
establishment or maintenance of epithelial cell apical/basal polarity
establishment or maintenance of polarity of embryonic epithelium
generation of neurons
morphogenesis of an epithelial sheet

Displaying entries **1 - 10** of 13 in total

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InterPro
Guanylate kinase, conserved site
Guanylate kinase-like domain
Guanylate kinase/L-type calcium channel beta subunit
L27 domain superfamily
L27 domain, C-terminal
L27 domain
L27-N
MPP5, SH3 domain
P-loop containing nucleoside triphosphate hydrolase
PDZ domain