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UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5

Summary

Gene Symbol

B4galt5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56336

KEGG Gene ID

mmu:56336

PubChem

56336

Alliance of Genome Resources

MGI:1927169

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid biosynthesis
Manganese
Metal-binding
Reference proteome
Signal-anchor
Sphingolipid metabolism
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9JMK0	Beta-1,4-GalT II Glucosylceramide beta-1,4-galactosyltransferase Lactosylceramide synthase UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5 UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5
Q3U7I0	Glucosylceramide beta-1,4-galactosyltransferase Lactosylceramide synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
ganglioside biosynthetic process	IMP
ganglioside biosynthetic process	IEA
carbohydrate metabolic process	IEA
sphingolipid metabolic process
glycoprotein biosynthetic process	IMP

GO Hierarchy

biological process

cellular process [inference]

ensheathment of neurons [inference]

axon ensheathment [inference]

axon ensheathment in central nervous system [inference]

central nervous system myelination

myelination [inference]

central nervous system myelination

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

poly-N-acetyllactosamine metabolic process [inference]

poly-N-acetyllactosamine biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

sphingolipid metabolic process

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

poly-N-acetyllactosamine metabolic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

cellular developmental process [inference]

cell maturation [inference]

neuron maturation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis [inference]

central nervous system neuron axonogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis [inference]

central nervous system neuron axonogenesis

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

neuron maturation

cellular developmental process [inference]

cell maturation [inference]

neuron maturation

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of embryonic development

positive regulation of multicellular organismal process [inference]

positive regulation of embryonic development

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of embryonic development

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

positive regulation of embryonic development

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of embryonic development

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

positive regulation of embryonic development

regulation of biological quality [inference]

regulation of protein stability

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Golgi apparatus	ISS
Golgi apparatus	IBA
Golgi apparatus	IEA
trans-Golgi network	IEA
Golgi cisterna membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

Golgi cisterna membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
N-acetyllactosamine synthase activity	IMP
UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	ISO
UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	IMP
UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	IBA
UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

UDP-galactosyltransferase activity [inference]

hexosyltransferase activity [inference]

galactosyltransferase activity [inference]

UDP-galactosyltransferase activity [inference]

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K09905

Name

beta-1,4-galactosyltransferase 5 [EC:2.4.1.274 2.4.1.-]

References

24498430

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R07617	2.4.1.-	G00033MO	G64973KT
R07628	2.4.1.-	G00041MO	G61730RY

Rhea

RHEA:31495

a β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine + UDP-α-D-galactose

H⁺ + a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + UDP

Enzyme

2.4.1.274

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000963
Gene Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	362275	RGD:1310062
Caenorhabditis elegans	190668	WB:WBGene00000269
Drosophila melanogaster	43425	FB:FBgn0039625
Drosophila melanogaster	36585	FB:FBgn0027538
Homo sapiens	9334	HGNC:928
Danio rerio	724080	ZFIN:ZDB-GENE-060628-3
Xenopus tropicalis	549139	Xenbase:XB-GENE-982971