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Guidelines

MIRAGE

platelet activating factor receptor

Summary

Gene Symbol

PTAFR

Organism

Homo sapiens (human)

External Links

NCBI Gene

5724

KEGG Gene ID

PubChem

5724

Alliance of Genome Resources

HGNC:9582

Annotation

Keyword

3D-structure
Cell membrane
Chemotaxis
Disulfide bond
G-protein coupled receptor
Glycoprotein
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P25105
A8K7N8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
chemotaxis	TAS
chemotaxis	IEA
inflammatory response	TAS
immune response	TAS
G protein-coupled receptor signaling pathway	TAS

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic nucleotide receptor signaling pathway

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

inositol phosphate metabolic process [inference]

inositol trisphosphate metabolic process [inference]

inositol trisphosphate biosynthetic process

inositol phosphate biosynthetic process [inference]

inositol trisphosphate biosynthetic process

organophosphate metabolic process [inference]

inositol phosphate metabolic process [inference]

inositol trisphosphate metabolic process [inference]

inositol trisphosphate biosynthetic process

inositol phosphate biosynthetic process [inference]

inositol trisphosphate biosynthetic process

organophosphate biosynthetic process [inference]

inositol phosphate biosynthetic process [inference]

inositol trisphosphate biosynthetic process

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

inositol phosphate biosynthetic process [inference]

inositol trisphosphate biosynthetic process

organophosphate biosynthetic process [inference]

inositol phosphate biosynthetic process [inference]

inositol trisphosphate biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

inositol phosphate metabolic process [inference]

inositol trisphosphate metabolic process [inference]

inositol trisphosphate biosynthetic process

inositol phosphate biosynthetic process [inference]

inositol trisphosphate biosynthetic process

polyol biosynthetic process [inference]

inositol phosphate biosynthetic process [inference]

inositol trisphosphate biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

inositol phosphate biosynthetic process [inference]

inositol trisphosphate biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

inositol phosphate biosynthetic process [inference]

inositol trisphosphate biosynthetic process

locomotion [inference]

taxis [inference]

chemotaxis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic nucleotide receptor signaling pathway

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
plasma membrane	IEA
membrane	NAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane

tertiary granule membrane

bounding membrane of organelle [inference]

secretory granule membrane

tertiary granule membrane

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
lipopolysaccharide binding	IEA
lipopolysaccharide immune receptor activity	IEA
G protein-coupled receptor activity	TAS
G protein-coupled receptor activity	IEA
platelet activating factor receptor activity	TAS

GO Hierarchy

molecular function

binding [inference]

protein binding

lipid binding [inference]

carbohydrate derivative binding [inference]

lipopolysaccharide binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

nucleotide receptor activity [inference]

purinergic nucleotide receptor activity [inference]

G protein-coupled purinergic nucleotide receptor activity

pattern recognition receptor activity [inference]

lipopolysaccharide immune receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

platelet activating factor receptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
G protein-coupled purinergic nucleotide receptor activity
chemotaxis
platelet activating factor receptor activity

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Platelet-activating factor receptor

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	19204	MGI:106066
Rattus norvegicus	58949	RGD:61897

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026