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Guidelines

MIRAGE

prostaglandin D2 receptor

Summary

Gene Symbol

PTGDR

Organism

Homo sapiens (human)

External Links

NCBI Gene

5729

PubChem

5729

Alliance of Genome Resources

HGNC:9591

Annotation

Keyword

Alternative splicing
Asthma
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Mast cell degranulation
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q13258	Prostanoid DP receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
mast cell degranulation	IEA
adenosine metabolic process	IEA
cellular response to prostaglandin D stimulus	IEA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte degranulation [inference]

mast cell degranulation

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

organonitrogen compound metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

organic substance metabolic process [inference]

carbohydrate derivative metabolic process [inference]

glycosyl compound metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

organonitrogen compound metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

reproductive process [inference]

developmental process involved in reproduction [inference]

sex determination [inference]

male sex determination

multicellular organismal process [inference]

sleep

developmental process [inference]

developmental process involved in reproduction [inference]

sex determination [inference]

male sex determination

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

response to lipid [inference]

response to prostaglandin [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

response to alcohol [inference]

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

response to ketone [inference]

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

response to ketone [inference]

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

establishment of localization in cell [inference]

leukocyte degranulation [inference]

mast cell degranulation

establishment of organelle localization [inference]

mast cell degranulation

organelle localization [inference]

establishment of organelle localization [inference]

mast cell degranulation

vacuolar localization [inference]

lysosome localization [inference]

mast cell degranulation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA	20959461
plasma membrane	IBA
membrane	NAS	7642548

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
prostaglandin J receptor activity	IEA
prostaglandin D receptor activity	NAS	7642548
prostaglandin D receptor activity	IBA
protein binding	IPI	20959461 32334026

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

prostaglandin receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

prostaglandin e2 receptor ep3 subtype

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
inflammatory response
positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Prostanoid receptor

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2841	asthma	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 72 in total

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Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	84023	FB:FBgn0036742
Drosophila melanogaster	292661	FB:FBgn0036742
Pan troglodytes	452906		PANTR08752
Rattus norvegicus	498475	Xenbase:XB-GENE-989130	RATNO10241
Canis lupus familiaris	610845		CANLF17913
Macaca mulatta	707918		MACMU41948
Sus scrofa	100127164		PIGXX15144
Callithrix jacchus	100392714		CALJA02213
Ailuropoda melanoleuca	100481528		AILME05280
Sus scrofa	100524418		PIGXX15144

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Last updated: August 4, 2025