GlyCosmos Portal

Submissions

prostaglandin E receptor 3

Summary

Gene Symbol

PTGER3

Organism

Homo sapiens (human)

External Links

NCBI Gene

5733

PubChem

5733

Alliance of Genome Resources

HGNC:9595

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
G-protein coupled receptor
Glycoprotein
Palmitate
Proteomics identification
Receptor
Reference proteome
Transducer
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P43115	PGE2-R Prostanoid EP3 receptor
O00325	Prostanoid EP3 receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
inflammatory response	IBA
G protein-coupled receptor signaling pathway	TAS	8307176
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA
phospholipase C-activating G protein-coupled receptor signaling pathway	IBA
positive regulation of cytosolic calcium ion concentration	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

cell death

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction [inference]

phasic smooth muscle contraction [inference]

intestine smooth muscle contraction

gastro-intestinal system smooth muscle contraction [inference]

intestine smooth muscle contraction

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of gastric acid secretion

regulation of gastric acid secretion [inference]

negative regulation of gastric acid secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of gastric acid secretion

positive regulation of biological process [inference]

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

positive regulation of multicellular organismal process [inference]

positive regulation of heat generation [inference]

positive regulation of fever generation

negative regulation of biological process [inference]

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of gastric acid secretion

negative regulation of multicellular organismal process [inference]

negative regulation of digestive system process [inference]

negative regulation of gastric acid secretion

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of fever generation [inference]

positive regulation of fever generation

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of fever generation [inference]

positive regulation of fever generation

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of heat generation [inference]

regulation of fever generation [inference]

positive regulation of fever generation

positive regulation of heat generation [inference]

positive regulation of fever generation

regulation of system process [inference]

regulation of digestive system process [inference]

regulation of gastric acid secretion [inference]

negative regulation of gastric acid secretion

negative regulation of digestive system process [inference]

negative regulation of gastric acid secretion

positive regulation of multicellular organismal process [inference]

positive regulation of heat generation [inference]

positive regulation of fever generation

negative regulation of multicellular organismal process [inference]

negative regulation of digestive system process [inference]

negative regulation of gastric acid secretion

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nuclear envelope	TAS	10336471
plasma membrane	TAS
plasma membrane	IDA	31097585
plasma membrane	IBA
membrane	NAS	9073510

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

Displaying **all 3** entries
GO Term	Evidence Code	PMID
prostaglandin E receptor activity	NAS	9073510
prostaglandin E receptor activity	IBA
protein binding	IPI	25416956

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

prostaglandin receptor activity [inference]

prostaglandin E receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

prostaglandin e2 receptor ep3 subtype

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
inflammatory response
positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Prostanoid receptor

Ortholog

Displaying entries **1 - 10** of 98 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	5729	FB:FBgn0036742
Drosophila melanogaster	5731	FB:FBgn0036742
Drosophila melanogaster	5732	FB:FBgn0036742
Xenopus tropicalis	5733	Xenbase:XB-GENE-987941
Drosophila melanogaster	5734	FB:FBgn0036742
Drosophila melanogaster	5737	FB:FBgn0036742
Drosophila melanogaster	5739	FB:FBgn0036742
Drosophila melanogaster	6915	FB:FBgn0036742
Drosophila melanogaster	19214	FB:FBgn0036742
Drosophila melanogaster	19216	FB:FBgn0036742