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Guidelines

MIRAGE

parathyroid hormone like hormone

Summary

Gene Symbol

PTHLH

Organism

Homo sapiens (human)

External Links

NCBI Gene

5744

KEGG Gene ID

PubChem

5744

Alliance of Genome Resources

HGNC:9607

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Cleavage on pair of basic residues
Cytoplasm
Direct protein sequencing
Disease variant
Hormone
Nucleus
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P12272	Parathyroid hormone-like protein
Q53XY9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
skeletal system development	IDA
osteoblast development	IBA
G protein-coupled receptor signaling pathway	IDA
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway

metabolic process [inference]

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cellular developmental process [inference]

cell development [inference]

osteoblast development

reproductive process [inference]

multi-organism reproductive process [inference]

female pregnancy

multicellular organismal process [inference]

multi-multicellular organism process [inference]

female pregnancy

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

osteoblast development

system development [inference]

skeletal system development

animal gross anatomical part developmental process [inference]

skeletal system development

tissue development [inference]

epidermis development

biomineral tissue development [inference]

bone mineralization

cellular developmental process [inference]

cell development [inference]

osteoblast development

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of chondrocyte development

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of chondrocyte development

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

negative regulation of multicellular organismal process [inference]

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of chondrocyte differentiation

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of chondrocyte development [inference]

negative regulation of chondrocyte development

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of chondrocyte development

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of chondrocyte development

regulation of chondrocyte development [inference]

negative regulation of chondrocyte development

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of chondrocyte development

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of multicellular organismal development [inference]

regulation of cartilage development [inference]

regulation of chondrocyte differentiation

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of chondrocyte development [inference]

negative regulation of chondrocyte development

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cell population proliferation [inference]

regulation of cell differentiation [inference]

regulation of chondrocyte differentiation

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of chondrocyte development [inference]

negative regulation of chondrocyte development

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of chondrocyte development

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of chondrocyte development

regulation of chondrocyte development [inference]

negative regulation of chondrocyte development

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of chondrocyte development

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of multicellular organismal development [inference]

regulation of cartilage development [inference]

regulation of chondrocyte differentiation

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

regulation of chondrocyte development [inference]

negative regulation of chondrocyte development

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

negative regulation of chondrocyte development

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
extracellular region	EXP
extracellular region	TAS
extracellular region	IDA
extracellular region	IEA
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **6 - 8** of 8 in total

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2
GO Term	Evidence Code	PMID
peptide hormone receptor binding	IDA
peptide hormone receptor binding	IBA
peptide hormone receptor binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

hormone receptor binding [inference]

peptide hormone receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110976	brachydactyly type E2	Alliance of Genome Resources

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Last updated: April 6, 2026