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dipeptidyl peptidase like 10

Summary

Gene Symbol

DPP10

Organism

Homo sapiens (human)

External Links

NCBI Gene

57628

PubChem

57628

Alliance of Genome Resources

HGNC:20823

Annotation

Keyword

3D-structure
Alternative splicing
Asthma
Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 5** entries
UniProt	Protein Name
Q0GLB9
B4DKB5
Q8N608	Dipeptidyl peptidase IV-related protein 3 Dipeptidyl peptidase X Dipeptidyl peptidase-like protein 2
B2RCJ8
Q0GLB7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proteolysis	IEA
protein localization to plasma membrane	ISS
regulation of potassium ion transmembrane transport	ISS
regulation of potassium ion transmembrane transport	IBA
positive regulation of protein localization to plasma membrane	IDA	15671030

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of potassium ion transport [inference]

regulation of potassium ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport

positive regulation of cellular process [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	IBA
voltage-gated potassium channel complex	IBA
voltage-gated potassium channel complex	IPI	27198182
membrane	IDA	12662155

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
serine-type peptidase activity	IEA
dipeptidyl-peptidase activity	IDA	12662155
potassium channel regulator activity	ISS
potassium channel regulator activity	IBA
transmembrane transporter binding	IPI	27198182

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

serine-type peptidase activity

exopeptidase activity [inference]

dipeptidyl-peptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

serine-type peptidase activity

exopeptidase activity [inference]

dipeptidyl-peptidase activity

binding [inference]

protein binding [inference]

transmembrane transporter binding

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

potassium channel regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

peptidase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
dipeptidyl-peptidase activity
proteolysis
serine-type peptidase activity

Displaying **all 3** entries
InterPro
Alpha/Beta hydrolase fold
Dipeptidylpeptidase IV, N-terminal domain
Peptidase S9, prolyl oligopeptidase, catalytic domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2841	asthma	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 69 in total

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Species	Gene ID	Orthologous MAtrix
Felis catus	101086917	FELCA18890
Ovis aries	101109248	SHEEP09559
Gorilla gorilla gorilla	101147291	GORGO27136
Oryzias latipes	101160516	ORYLA09358
Tursiops truncatus	101332296	TURTR14172
Mustela putorius furo	101676587	MUSPF04446
Heterocephalus glaber	101716881	HETGA09247
Melopsittacus undulatus	101879553	MELUD00326
Ictidomys tridecemlineatus	101957279	ICTTR10189
Chinchilla lanigera	102028831	CHILA15096