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RAD51 paralog B

Summary

Gene Symbol

RAD51B

Organism

Homo sapiens (human)

External Links

NCBI Gene

5890

PubChem

5890

Alliance of Genome Resources

HGNC:9822

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Chromosomal rearrangement
DNA recombination
DNA repair
DNA-binding
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O15315	RAD51 homolog B RAD51-like protein 1
C9JYJ0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
double-strand break repair via homologous recombination	IMP	23149936
double-strand break repair via homologous recombination	IBA
blastocyst growth	IEA
DNA repair	TAS	9512535
DNA recombination	TAS	9512535

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

cellular process [inference]

cell cycle process [inference]

meiotic cell cycle process [inference]

reciprocal meiotic recombination

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination

recombinational repair [inference]

double-strand break repair via homologous recombination

homologous recombination [inference]

reciprocal homologous recombination [inference]

reciprocal meiotic recombination

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

reproductive process [inference]

meiotic cell cycle process [inference]

reciprocal meiotic recombination

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

somite development

growth [inference]

developmental growth [inference]

blastocyst growth

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle process [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	TAS	9512535
nucleoplasm	TAS
replication fork	IDA	20207730
replication fork	IBA
Rad51B-Rad51C-Rad51D-XRCC2 complex	IDA	11751635

GO Hierarchy

cellular component

protein-containing complex [inference]

DNA recombinase mediator complex [inference]

Rad51B-Rad51C-Rad51D-XRCC2 complex

nuclear protein-containing complex [inference]

Rad51B-Rad51C-Rad51D-XRCC2 complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
four-way junction DNA binding	IDA	20207730
four-way junction DNA binding	IBA
DNA binding	TAS	9512535
double-stranded DNA binding	IDA	12441335
double-stranded DNA binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA

ATP-dependent DNA damage sensor activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

DNA secondary structure binding [inference]

four-way junction DNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

small molecule sensor activity [inference]

DNA damage sensor activity [inference]

ATP-dependent DNA damage sensor activity

ATP-dependent activity [inference]

ATP-dependent activity, acting on DNA

ATP-dependent DNA damage sensor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

protein

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ATP binding
ATP-dependent DNA damage sensor activity
DNA repair
four-way junction DNA binding

Displaying **all 2** entries
InterPro
DNA recombination and repair protein RecA-like, ATP-binding domain
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **1 - 10** of 43 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	5890	ZFIN:ZDB-GENE-040426-2750
Mus musculus	19363		MOUSE09294
Danio rerio	406721		DANRE18683
Pan troglodytes	467487		PANTR09021
Rattus norvegicus	500679		RATNO36712
Bos taurus	617007		BOVIN01608
Equus caballus	100053023		HORSE22580
Taeniopygia guttata	100225762		TAEGU24854
Callithrix jacchus	100404195		CALJA01535
Pongo abelii	100446521		PONAB08496

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OrthoDB (Group)

International Collaboration

Acknowledgements