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RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Summary

Gene Symbol

Rfng

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

60433

KEGG Gene ID

rno:60433

PubChem

60433

Alliance of Genome Resources

RGD:621322

Annotation

Keyword

Developmental protein
Differentiation
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Neurogenesis
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 5** entries
UniProt	Protein Name
Q9R1U9	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
A6HLJ5	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
A0A0G2K5T8	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Q6P6T7	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
M0RD65	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
pattern specification process	IEA
nervous system development	IEA
regulation of Notch signaling pathway	ISS
regulation of Notch signaling pathway	ISO
regulation of Notch signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation

multicellular organismal process [inference]

pattern specification process

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	ISS
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	ISO
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	IBA
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	IEA
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

beta-1,3-n-acetylglucosaminyltransferase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
regulation of Notch signaling pathway
transferase activity

Displaying 1 entry
InterPro
Fringe-like, glycosyltransferase domain

KEGG BRITE Database

Orthology

K05948

Name

fringe [EC:2.4.1.222]

References

9187150

Rhea

RHEA:70511

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.222

PMID

RHEA:70531

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.222

PMID

Ortholog

Displaying entries **31 - 40** of 63 in total

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Species	Gene ID	Orthologous MAtrix
Latimeria chalumnae	102362901	LATCH18311
Pelodiscus sinensis	102455692	PELSI04678
Astyanax mexicanus	103037421	ASTMX16448
Carlito syrichta	103251328	CARSF17739
Nannospalax galili	103730070	NANGA18354
Macaca nemestrina	105469329	MACNE15498
Mandrillus leucophaeus	105552392	MANLE00397
Cercocebus atys	105588569	CERAT39546
Aotus nancymaae	105717461	AOTNA34286
Propithecus coquereli	105820019	PROCO28431

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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OrthoDB (Group)

KEGG BRITE Database

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Acknowledgements