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PR/SET domain 1

Summary

Gene Symbol

PRDM1

Organism

Homo sapiens (human)

External Links

NCBI Gene

639

PubChem

639

Alliance of Genome Resources

HGNC:9346

JoGo

PRDM1

TogoVar

PRDM1

Annotation

Keyword

3D-structure
Adaptive immunity
Alternative splicing
Cytoplasm
DNA-binding
Innate immunity
Isopeptide bond
Methyltransferase
Nucleus
Proteomics identification
Reference proteome
Repeat
Repressor
S-adenosyl-L-methionine
Transcription regulation
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A3B3IU23
O75626	BLIMP-1 Beta-interferon gene positive regulatory domain I-binding factor PR domain-containing protein 1 Positive regulatory domain I-binding factor 1
B4DW27
Q5T4E8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 35 in total

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GO Term	Evidence Code	PMID
negative regulation of transcription by RNA polymerase II	TAS	1851123
negative regulation of transcription by RNA polymerase II	IDA	1851123
negative regulation of transcription by RNA polymerase II	IEA	http://purl.obolibrary.org/obo/go/references/0000117
morphogenesis of a branching structure
kidney development

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

methylation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cell population proliferation [inference]

epithelial cell proliferation [inference]

sebum secreting cell proliferation

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

cellular developmental process

cell differentiation [inference]

neuron differentiation [inference]

glutamatergic neuron differentiation [inference]

retinal bipolar neuron differentiation

cell differentiation involved in embryonic placenta development [inference]

trophoblast giant cell differentiation

cell fate commitment

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

intestinal epithelial cell development

germ cell development

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development

reproductive process [inference]

developmental process involved in reproduction [inference]

cell differentiation involved in embryonic placenta development [inference]

trophoblast giant cell differentiation

multicellular organismal reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

maternal process involved in female pregnancy [inference]

maternal placenta development

multicellular organismal process [inference]

developmental process [inference]

developmental process involved in reproduction [inference]

cell differentiation involved in embryonic placenta development [inference]

trophoblast giant cell differentiation

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis

anatomical structure development [inference]

blood vessel development [inference]

artery development [inference]

aorta development

coronary vasculature development

cardiac septum development [inference]

ventricular septum development

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

intestinal epithelial cell development

germ cell development

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development

animal organ development [inference]

kidney development

cellular developmental process

cell differentiation [inference]

neuron differentiation [inference]

glutamatergic neuron differentiation [inference]

retinal bipolar neuron differentiation

cell differentiation involved in embryonic placenta development [inference]

trophoblast giant cell differentiation

cell fate commitment

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

intestinal epithelial cell development

germ cell development

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

immune response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

regulation of natural killer cell differentiation

regulation of lymphocyte differentiation [inference]

regulation of natural killer cell differentiation

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of alpha-beta T cell activation [inference]

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of natural killer cell differentiation

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of natural killer cell differentiation

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of natural killer cell differentiation

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cell population proliferation

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of natural killer cell differentiation

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

regulation of natural killer cell differentiation

regulation of lymphocyte differentiation [inference]

regulation of natural killer cell differentiation

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of alpha-beta T cell activation [inference]

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

regulation of natural killer cell differentiation

regulation of lymphocyte differentiation [inference]

regulation of natural killer cell differentiation

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of alpha-beta T cell activation [inference]

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of natural killer cell differentiation

regulation of T cell differentiation [inference]

regulation of extrathymic T cell differentiation

regulation of alpha-beta T cell differentiation [inference]

regulation of NK T cell differentiation

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GO Term	Evidence Code	PMID
nucleus	IDA	28842558
nucleus	IBA	http://purl.obolibrary.org/obo/go/references/0000033
nucleus	IEA	http://purl.obolibrary.org/obo/go/references/0000044 http://purl.obolibrary.org/obo/go/references/0000107 http://purl.obolibrary.org/obo/go/references/0000117
nucleoplasm	TAS	https://reactome.org/content/detail/R-HSA-6804193 https://reactome.org/content/detail/R-HSA-6804194 https://reactome.org/content/detail/R-HSA-9701548 https://reactome.org/content/detail/R-HSA-9827872 https://reactome.org/content/detail/R-HSA-9828027
nucleoplasm	IDA	http://purl.obolibrary.org/obo/go/references/0000052

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nucleolus

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
transcription cis-regulatory region binding	IEA	http://purl.obolibrary.org/obo/go/references/0000117
RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA	http://purl.obolibrary.org/obo/go/references/0000104
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	1851123
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	http://purl.obolibrary.org/obo/go/references/0000033
DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	1851123