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polypeptide N-acetylgalactosaminyltransferase 11

Summary

Gene Symbol

GALNT11

Aliases

GalNAc-T11
polypeptide GalNAc transferase 11

Organism

Homo sapiens (human)

External Links

NCBI Gene

63917

GGDB ID

gg097

HGNC

19875

mRNA

NM_022087

map

7q34-q36

Protein

NP_071370

OMIM

615130

KEGG Gene ID

hsa:63917

PubChem

63917

Alliance of Genome Resources

HGNC:19875

JoGo

GALNT11

TogoVar

GALNT11

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Heterotaxy
Lectin
Manganese
Metal-binding
Notch signaling pathway
Phosphoprotein
Proteomics identification
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q8NCW6	Polypeptide GalNAc transferase 11 Protein-UDP acetylgalactosaminyltransferase 11 UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11
B7Z5G5	Protein-UDP acetylgalactosaminyltransferase
A0A090N7X6	Protein-UDP acetylgalactosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
protein O-linked glycosylation	IBA
Notch signaling pathway
Notch receptor processing	ISS
determination of left/right symmetry	ISS
regulation of Notch signaling pathway	ISS

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

Notch signaling involved in heart development

cell surface receptor signaling pathway involved in heart development [inference]

Notch signaling involved in heart development

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

protein metabolic process [inference]

Notch receptor processing

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

primary metabolic process [inference]

protein metabolic process [inference]

Notch receptor processing

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via N-acetyl-galactosamine

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

multicellular organismal process [inference]

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

Notch signaling involved in heart development

cell surface receptor signaling pathway involved in heart development [inference]

Notch signaling involved in heart development

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
Golgi membrane	TAS
Golgi membrane	IEA
Golgi apparatus	IDA
Golgi apparatus	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
polypeptide N-acetylgalactosaminyltransferase activity	TAS
polypeptide N-acetylgalactosaminyltransferase activity	IDA
polypeptide N-acetylgalactosaminyltransferase activity	IBA
polypeptide N-acetylgalactosaminyltransferase activity	IEA
Notch binding	IDA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

hexosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

catalytic activity, acting on a protein [inference]

polypeptide N-acetylgalactosaminyltransferase activity

binding [inference]

protein binding

signaling receptor binding [inference]

Notch binding

carbohydrate binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

N-acetylgalactosaminyltransferase

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
polypeptide N-acetylgalactosaminyltransferase activity
protein O-linked glycosylation
transferase activity

Displaying **all 5** entries
InterPro
Glycosyltransferase 2-like
N-acetylgalactosaminyltransferase
Nucleotide-diphospho-sugar transferases
Ricin B, lectin domain
Ricin B-like lectins

Human Protein Atlas

ENSG00000178234

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg097

Gene Symbol

GALNT11

Orthologous Gene

Displaying **all 4** entries
Species	Protein	mRNA
Caenorhabditis elegans	NP_499582	NM_067181
Mus musculus	NP_659157	NM_144908
Drosophila melanogaster	NP_652069	NM_143812
Rattus norvegicus	NP_955425	NM_199393

KEGG BRITE Database

Orthology

K00710

Name

polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]

References

9295285

Rhea

RHEA:23956

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

RHEA:52424

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	231050	MGI:2444392
Rattus norvegicus	311952	RGD:735097
Caenorhabditis elegans	176647	WB:WBGene00001636
Drosophila melanogaster	48775	FB:FBgn0001970
Danio rerio	558716	ZFIN:ZDB-GENE-060929-998
Xenopus laevis	447314	Xenbase:XB-GENE-981834
Xenopus laevis	100158361	Xenbase:XB-GENE-17335711
Xenopus tropicalis	448751	Xenbase:XB-GENE-981830

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

GlycoGene Database (GGDB)

KEGG BRITE Database

International Collaboration

Acknowledgements