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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

solute carrier family 22 member 4

Summary

Gene Symbol

Slc22a4

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

64037

KEGG Gene ID

PubChem

64037

Alliance of Genome Resources

RGD:621149

Annotation

Keyword

ATP-binding
Cell membrane
Glycoprotein
Ion transport
Mitochondrion
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6HEF8
Q9R141	Organic cation/carnitine transporter 1
A6HEG0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
sulfur amino acid transport	IDA
triglyceride metabolic process	ISO
sodium ion transport
neurotransmitter transport	IEA
lactation	IEP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

carnitine metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

transmembrane transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

sodium-independent organic anion transport

import across plasma membrane [inference]

amino acid import across plasma membrane

carnitine transmembrane transport

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration [inference]

liver regeneration

animal gross anatomical part developmental process [inference]

animal organ development [inference]

animal organ regeneration [inference]

liver regeneration

gland development [inference]

liver development [inference]

liver regeneration

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin D

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin D

response to lipid [inference]

response to nitrogen compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

response to oxygen-containing compound [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

neurotransmitter transport

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

sulfur amino acid transport

xenobiotic transport

secretion [inference]

body fluid secretion [inference]

lactation

transmembrane transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

sodium-independent organic anion transport

import across plasma membrane [inference]

amino acid import across plasma membrane

carnitine transmembrane transport

nitrogen compound transport [inference]

sulfur amino acid transport

quaternary ammonium group transport

amino-acid betaine transport [inference]

carnitine transport

carnitine transmembrane transport

acetylcholine transport [inference]

acetylcholine uptake

modified amino acid transport [inference]

amino-acid betaine transport [inference]

carnitine transport

carnitine transmembrane transport

sulfur compound transport [inference]

sulfur amino acid transport

import into cell [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

acetate ester transport [inference]

acetylcholine transport [inference]

acetylcholine uptake

biological regulation [inference]

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion [inference]

lactation

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	IDA
mitochondrion	IEA
plasma membrane	IBA
basal plasma membrane	ISS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

endomembrane system

plasma membrane

organelle membrane [inference]

mitochondrial membrane

plasma membrane region [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

cell body [inference]

neuronal cell body

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
acetylcholine transmembrane transporter activity	ISS
acetylcholine transmembrane transporter activity	ISO
acetylcholine transmembrane transporter activity	IEA
ATP binding	IEA
obsolete organic cation transmembrane transporter activity

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

neurotransmitter transmembrane transporter activity [inference]

acetylcholine transmembrane transporter activity

amino acid transmembrane transporter activity

quaternary ammonium group transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity

modified amino acid transmembrane transporter activity [inference]

acetate ester transmembrane transporter activity [inference]

acetylcholine transmembrane transporter activity

binding [inference]

protein binding [inference]

protein domain specific binding [inference]

PDZ domain binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	6583	HGNC:10968
Caenorhabditis elegans	172841	WB:WBGene00003842
Mus musculus	30805	MGI:1353479
Saccharomyces cerevisiae S288C	850462	SGD:S000000695

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026