nucleotide binding oligomerization domain containing 2

Summary
Gene Symbol
  • NOD2
Organism
Homo sapiens (human)
NCBI Gene
64127
KEGG Gene ID
[""]
PubChem
64127
Alliance of Genome Resources
Annotation
Keyword
  • ATP-binding
  • Adaptive immunity
  • Alternative initiation
  • Autophagy
  • Cell membrane
  • Cytoplasm
  • Disease variant
  • Glycoprotein
  • Innate immunity
  • Leucine-rich repeat
  • Mitochondrion
  • Palmitate
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Ubl conjugation
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A286YF65
  • Caspase recruitment domain-containing protein 15
Q9HC29
  • Caspase recruitment domain-containing protein 15
  • Inflammatory bowel disease protein 1
Gene Ontology (GO)
GO Hierarchy
Displaying entries 1 - 5 of 18 in total
GO Term Evidence Code PMID
actin binding
protein binding
ATP binding
enzyme binding
protein kinase binding
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
lrr and pyd
Functional Category
  • M: Cell wall/membrane/envelope biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying entries 1 - 10 of 26 in total
DO ID Disease Name Source
DOID:0050678 Blau syndrome
DOID:0050861 colorectal adenocarcinoma
DOID:0050922 gastrointestinal carcinoma
DOID:0080176 meningococcal meningitis
DOID:0081267 graft-versus-host disease
DOID:0081451 PFAPA syndrome
DOID:1024 leprosy
DOID:1324 lung cancer
DOID:13241 Behcet's disease
DOID:13406 pulmonary sarcoidosis

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026