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Repository for lectin-assisted multimodality data

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Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

biliverdin reductase A

Summary

Gene Symbol

BLVRA

Organism

Homo sapiens (human)

External Links

NCBI Gene

644

KEGG Gene ID

PubChem

644

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
Direct protein sequencing
Metal-binding
NAD
NADP
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P53004	Biliverdin-IX alpha-reductase
A0A140VJF4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
MAPK cascade
glycogen metabolic process
apoptotic DNA fragmentation
fatty acid metabolic process
triglyceride metabolic process

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

immune response

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

complement component C5a signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

reactive oxygen species biosynthetic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

heme metabolic process [inference]

heme catabolic process

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme catabolic process

pigment metabolic process [inference]

heme metabolic process [inference]

heme catabolic process

pigment catabolic process [inference]

heme catabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

insulin metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

lipid metabolic process [inference]

fatty acid metabolic process

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

lipid modification [inference]

lipid oxidation

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

protein metabolic process [inference]

insulin metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

reactive oxygen species metabolic process [inference]

reactive oxygen species biosynthetic process

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of itch

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

sensory organ development [inference]

ear development

locomotion [inference]

taxis [inference]

chemotaxis

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to oxidative stress

immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to nutrient levels [inference]

response to food

response to chemical [inference]

response to food

response to lipid [inference]

response to lipopolysaccharide

response to nitrogen compound [inference]

response to cyclosporin A

response to oxygen-containing compound [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway [inference]

complement component C5a signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

complement component C5a signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleus	IEA
cytoplasm	IEA
cytosol	TAS
cytosol	IDA
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
nucleotide binding	IEA
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
biliverdin reductase [NAD(P)H] activity	IDA
biliverdin reductase [NAD(P)H] activity	IBA
biliverdin reductase [NAD(P)H] activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [inference]

biliverdin reductase [NAD(P)H] activity

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

heterocyclic compound binding [inference]

nucleotide binding

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026