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protein disulfide isomerase family A member 2

Summary

Gene Symbol

PDIA2

Organism

Homo sapiens (human)

External Links

NCBI Gene

64714

KEGG Gene ID

PubChem

64714

Alliance of Genome Resources

HGNC:14180

Annotation

Keyword

Alternative splicing
Chaperone
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Isomerase
Proteomics identification
Redox-active center
Reference proteome
Repeat
Signal
Steroid-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
Q13087	Pancreas-specific protein disulfide isomerase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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2

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GO Term	Evidence Code	PMID
protein folding	TAS
protein folding	IBA
protein retention in ER lumen	TAS
protein folding in endoplasmic reticulum	TAS
protein folding in endoplasmic reticulum	IEA

GO Hierarchy

biological process

cellular process [inference]

protein folding

protein folding in endoplasmic reticulum

cell adhesion [inference]

cell-cell adhesion [inference]

homotypic cell-cell adhesion [inference]

platelet aggregation

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein localization in endoplasmic reticulum [inference]

protein retention in ER lumen

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

localization [inference]

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein localization in endoplasmic reticulum [inference]

protein retention in ER lumen

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein localization in endoplasmic reticulum [inference]

protein retention in ER lumen

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	TAS
endoplasmic reticulum	IBA
endoplasmic reticulum lumen	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 7 in total

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2

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GO Term	Evidence Code	PMID
protein disulfide isomerase activity	TAS
protein disulfide isomerase activity	IBA
steroid binding
protein binding	IPI
protein-disulfide reductase activity	IDA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

disulfide oxidoreductase activity

protein-disulfide reductase activity

isomerase activity [inference]

intramolecular oxidoreductase activity [inference]

intramolecular oxidoreductase activity, transposing S-S bonds [inference]

protein disulfide isomerase activity

catalytic activity, acting on a protein [inference]

binding [inference]

protein binding

lipid binding [inference]

steroid binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	69191	MGI:1916441
Caenorhabditis elegans	180724	WB:WBGene00003963
Saccharomyces cerevisiae S288C	850314	SGD:S000000548
Saccharomyces cerevisiae S288C	852130	SGD:S000002926