PTEN induced kinase 1

Summary
Gene Symbol
  • PINK1
Organism
Homo sapiens (human)
NCBI Gene
65018
KEGG Gene ID
[""]
PubChem
65018
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Alternative splicing
  • Autophagy
  • Cytoplasm
  • Disease variant
  • Magnesium
  • Metal-binding
  • Mitochondrion inner membrane
  • Mitochondrion outer membrane
  • Neurodegeneration
  • Parkinson disease
  • Parkinsonism
  • Phosphoprotein
  • Primary mitochondrial disease
  • Proteomics identification
  • Reference proteome
  • Serine/threonine-protein kinase
  • Transit peptide
Proteins
Displaying 1 entry
UniProt Protein Name
Q9BXM7
  • BRPK
  • PTEN-induced putative kinase protein 1
Gene Ontology (GO)
Displaying entries 1 - 5 of 89 in total
GO Term Evidence Code PMID
autophagy of mitochondrion
autophagy of mitochondrion
mitophagy
mitophagy
mitophagy
GO Hierarchy
Displaying entries 1 - 5 of 32 in total
GO Term Evidence Code PMID
chromatin
nucleus
cytoplasm
mitochondrion
mitochondrion
Displaying entries 1 - 5 of 28 in total
GO Term Evidence Code PMID
magnesium ion binding
magnesium ion binding
protease binding
protease binding
protein kinase activity
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
protein kinase
Functional Category
  • E: Amino acid transport and metabolism
  • G: Carbohydrate transport and metabolism
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0060369 Parkinson's disease 6
DOID:14330 Parkinson's disease

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026