GlyCosmos Portal

Submissions

matrix metallopeptidase 16

Summary

Gene Symbol

Mmp16

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

65205

PubChem

65205

Alliance of Genome Resources

RGD:620199

Annotation

Keyword

Alternative splicing
Calcium
Cell membrane
Cleavage on pair of basic residues
Collagen degradation
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Repeat
Signal
Transmembrane helix
Zinc
Zymogen

Proteins

Displaying **all 3** entries
UniProt	Protein Name
O35548	Membrane-type matrix metalloproteinase 3 Membrane-type-3 matrix metalloproteinase
F1M7F5
A6IIB9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
skeletal system development	IBA	http://purl.obolibrary.org/obo/go/references/0000033
ossification	ISO	http://purl.obolibrary.org/obo/go/references/0000121
endochondral ossification	ISO	http://purl.obolibrary.org/obo/go/references/0000121
proteolysis	ISO	http://purl.obolibrary.org/obo/go/references/0000121
proteolysis	IEA	http://purl.obolibrary.org/obo/go/references/0000002

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

collagen catabolic process

collagen metabolic process [inference]

collagen catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

protein maturation [inference]

protein processing

cell population proliferation [inference]

chondrocyte proliferation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

multicellular organismal process [inference]

ossification

replacement ossification [inference]

endochondral ossification

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

skeletal system morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

craniofacial suture morphogenesis

anatomical structure development [inference]

animal organ development [inference]

bone development

system development [inference]

skeletal system development

response to stimulus [inference]

response to chemical [inference]

response to odorant

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
extracellular region	IBA
obsolete extracellular space
plasma membrane	ISO	http://purl.obolibrary.org/obo/go/references/0000121
plasma membrane	IBA	http://purl.obolibrary.org/obo/go/references/0000033
plasma membrane	IEA	http://purl.obolibrary.org/obo/go/references/0000044 http://purl.obolibrary.org/obo/go/references/0000107

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
metalloendopeptidase activity	ISO	http://purl.obolibrary.org/obo/go/references/0000121
metalloendopeptidase activity	IBA
metalloendopeptidase activity	IEA	http://purl.obolibrary.org/obo/go/references/0000002 http://purl.obolibrary.org/obo/go/references/0000107
metallopeptidase activity	IEA
zinc ion binding	ISO	http://purl.obolibrary.org/obo/go/references/0000121

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity [inference]

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity [inference]

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

matrix metalloproteinase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
collagen catabolic process
extracellular matrix organization
hydrolase activity
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis
zinc ion binding

Displaying **all 10** entries
InterPro
Hemopexin-like domain superfamily
Hemopexin-like domain
Hemopexin-like repeats
Metallopeptidase, catalytic domain superfamily
PGBD-like superfamily
Peptidase M10, metallopeptidase
Peptidase M10A, catalytic domain
Peptidase M10A
Peptidase, metallopeptidase
Peptidoglycan binding-like