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MIRAGE
solute carrier family 5 member 1
Summary
- Gene Symbol
-
- SLC5A1
- Aliases
-
- D22S675
- NAGT
- SGLT-1
- sodium/glucose cotransporter 1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Sodium transport
- Sugar transport
- Symport
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P13866 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| alpha-glucoside transport |
|
|
| alpha-glucoside transport |
|
|
| alpha-glucoside transport |
|
|
| intestinal D-glucose absorption |
|
|
| sodium ion transport |
|
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| early endosome |
|
|
| Golgi apparatus |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| galactose transmembrane transporter activity |
|
|
| myo-inositol:sodium symporter activity |
|
|
| water transmembrane transporter activity |
|
|
| D-glucose:sodium symporter activity |
|
|
| D-glucose:sodium symporter activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- solute carrier family 5 member 5
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| InterPro |
|---|
| Sodium/glucose symporter superfamily |
| Sodium/solute symporter |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070563 | glucose-galactose malabsorption |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000083 | Renal insufficiency |
| HP:0000787 | Nephrolithiasis |
| HP:0000790 | Hematuria |
| HP:0001508 | Failure to thrive |
| HP:0001824 | Weight loss |
| HP:0001942 | Metabolic acidosis |
| HP:0001944 | Dehydration |
| HP:0001945 | Fever |
| HP:0001986 | Hypertonic dehydration |
| Disease ID | Disease Name |
|---|---|
| OMIM:606824 |
|
| ORPHA:35710 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 20537 | MGI:107678 | |
| 25552 | RGD:3713 |
