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solute carrier family 6 member 1

Summary

Gene Symbol

SLC6A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

6529

KEGG Gene ID

PubChem

6529

Alliance of Genome Resources

HGNC:11042

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Disease variant
Disulfide bond
Epilepsy
Glycoprotein
Metal-binding
Neurotransmitter transport
Phosphoprotein
Proteomics identification
Reference proteome
Sodium
Symport
Synapse
Transmembrane helix
Transport

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A2R8Y4I3
B7Z3C5
P30531	Solute carrier family 6 member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
amino acid transmembrane transport	IEA
neurotransmitter transport	TAS
neurotransmitter transport	IEA
amino acid transport	IBA
chemical synaptic transmission	TAS

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

transmembrane transport [inference]

amino acid transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic anion import across plasma membrane

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning

memory

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning

memory

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

neurotransmitter transport

neurotransmitter uptake [inference]

neurotransmitter reuptake

amino acid neurotransmitter reuptake [inference]

gamma-aminobutyric acid reuptake

amino acid transport

amino acid transmembrane transport

acidic amino acid transport [inference]

gamma-aminobutyric acid import

gamma-aminobutyric acid transport [inference]

amino acid neurotransmitter reuptake [inference]

gamma-aminobutyric acid reuptake

vascular transport [inference]

transport across blood-brain barrier

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

inorganic anion import across plasma membrane

organic anion transport [inference]

carboxylic acid transport [inference]

gamma-aminobutyric acid transport [inference]

organic acid transport [inference]

carboxylic acid transport [inference]

gamma-aminobutyric acid transport [inference]

transmembrane transport [inference]

amino acid transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic anion import across plasma membrane

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

nitrogen compound transport [inference]

gamma-aminobutyric acid transport [inference]

import into cell [inference]

neurotransmitter uptake [inference]

neurotransmitter reuptake

amino acid neurotransmitter reuptake [inference]

gamma-aminobutyric acid reuptake

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic anion import across plasma membrane

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

establishment of localization in cell [inference]

neurotransmitter reuptake

amino acid neurotransmitter reuptake [inference]

gamma-aminobutyric acid reuptake

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane

plasma membrane

cell junction [inference]

synapse [inference]

GABA-ergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

cell body [inference]

neuronal cell body

presynapse

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
amino acid:sodium symporter activity	IEA
gamma-aminobutyric acid:sodium:chloride symporter activity	TAS
gamma-aminobutyric acid:sodium:chloride symporter activity	IDA
gamma-aminobutyric acid:sodium:chloride symporter activity	IMP
gamma-aminobutyric acid:sodium:chloride symporter activity	IBA