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solute carrier family 34 member 1

Summary

Gene Symbol

SLC34A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

6569

KEGG Gene ID

PubChem

6569

Alliance of Genome Resources

HGNC:11019

Annotation

Keyword

Alternative splicing
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Osteoporosis
Phosphoprotein
Proteomics identification
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q86VN6	Na(+)-dependent phosphate cotransporter 2A Sodium/phosphate cotransporter 2A Solute carrier family 34 member 1
Q7Z725	Na(+)-dependent phosphate cotransporter 2A Sodium/phosphate cotransporter 2A Solute carrier family 34 member 1
Q06495	Na(+)-dependent phosphate cotransporter 2A NaPi-3 Sodium/phosphate cotransporter 2A Solute carrier family 34 member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 37 in total

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GO Term	Evidence Code	PMID
ossification	IEA
kidney development	IEA
phosphate ion transport	IDA
response to nutrient	IEA
glycoprotein metabolic process

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

indole-containing compound metabolic process [inference]

indole metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

gentamycin metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process

glycoside metabolic process [inference]

gentamycin metabolic process

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

cellular response to metal ion

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

phosphate ion transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

arsenate ion transmembrane transport

multicellular organismal process [inference]

ossification

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

odontogenesis [inference]

odontogenesis of dentin-containing tooth [inference]

dentinogenesis

anatomical structure formation involved in morphogenesis [inference]

dentinogenesis

anatomical structure development [inference]

animal organ development [inference]

kidney development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular phosphate ion homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular phosphate ion homeostasis

inorganic ion homeostasis [inference]

phosphate ion homeostasis

intracellular phosphate ion homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

response to peptide hormone

response to growth hormone

response to parathyroid hormone

cellular response to parathyroid hormone stimulus

response to thyroid hormone

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

response to nutrient levels [inference]

response to nutrient

response to vitamin [inference]

response to vitamin A

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to chemical [inference]

response to nutrient

response to vitamin [inference]

response to vitamin A

response to xenobiotic stimulus

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

response to peptide hormone

response to growth hormone

response to parathyroid hormone

cellular response to parathyroid hormone stimulus

response to thyroid hormone

response to metal ion [inference]

response to lipid [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

cellular response to metal ion

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

response to peptide

response to nitrogen compound [inference]

response to alkaloid [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

response to staurosporine [inference]

cellular response to staurosporine

response to peptide hormone

response to growth hormone

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

response to oxygen-containing compound [inference]

response to estradiol

response to peptide hormone

response to growth hormone

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

cellular response to metal ion

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

inorganic anion transport [inference]

phosphate ion transport

arsenite transport [inference]

arsenate ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

phosphate ion transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

arsenate ion transmembrane transport

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of phosphate transport [inference]

regulation of sodium-dependent phosphate transport [inference]

positive regulation of sodium-dependent phosphate transport

regulation of phosphate transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of phosphate transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of sodium-dependent phosphate transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of sodium-dependent phosphate transport

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of phosphate transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of biological quality [inference]

regulation of membrane potential [inference]

positive regulation of membrane potential

Displaying entries **11 - 15** of 21 in total

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GO Term	Evidence Code	PMID
membrane	IEA
apical plasma membrane	IDA
apical plasma membrane	IBA
apical plasma membrane	IEA
nuclear speck

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

membraneless organelle [inference]

intracellular membraneless organelle [inference]

spindle [inference]

mitotic spindle

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membraneless organelle [inference]

spindle [inference]

mitotic spindle

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

perinuclear region of cytoplasm

cluster of actin-based cell projections [inference]

brush border

supramolecular complex [inference]

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
sodium:phosphate symporter activity	TAS
sodium:phosphate symporter activity	IDA
sodium:phosphate symporter activity	IMP
sodium:phosphate symporter activity	IBA
sodium:phosphate symporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

phosphate transmembrane transporter activity [inference]

sodium:phosphate symporter activity

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

binding [inference]

protein binding

protein domain specific binding [inference]

PDZ domain binding

identical protein binding

protein-containing complex binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:0080077	hypophosphatemic nephrolithiasis/osteoporosis 1	Alliance of Genome Resources
DOID:0080758	Fanconi renotubular syndrome 2	Alliance of Genome Resources
DOID:0050947	hereditary hypophosphatemic rickets with hypercalciuria	Alliance of Genome Resources
DOID:784	chronic kidney disease	Alliance of Genome Resources
DOID:585	nephrolithiasis	Alliance of Genome Resources
DOID:12678	hypercalcemia	Alliance of Genome Resources
DOID:1062	Fanconi syndrome	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	20505	MGI:1345284
Rattus norvegicus	25548	RGD:3708

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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