synuclein alpha

Summary
Gene Symbol
  • SNCA
Organism
Homo sapiens (human)
NCBI Gene
6622
PubChem
6622
Alliance of Genome Resources
JoGo
SNCA
TogoVar
SNCA
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Alzheimer disease
  • Amyloid
  • Cell projection
  • Copper
  • Cytoplasm
  • Direct protein sequencing
  • Disease variant
  • Membrane
  • Metal-binding
  • Neurodegeneration
  • Nucleus
  • Parkinson disease
  • Parkinsonism
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Secreted
  • Synapse
  • Ubl conjugation
Proteins
Displaying all 2 entries
UniProt Protein Name
H6UYS5
P37840
  • Non-A beta component of AD amyloid
  • Non-A4 component of amyloid precursor
Gene Ontology (GO)
GO Hierarchy
Displaying entries 1 - 5 of 48 in total
GO Term Evidence Code PMID
extracellular region
extracellular region
extracellular region
obsolete extracellular space
nucleus
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
synuclein alpha
Functional Category
  • K: Transcription
  • P: Inorganic ion transport and metabolism
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:0060367 Parkinson's disease 1
DOID:0060895 Parkinson's disease 4
DOID:10652 Alzheimer's disease
DOID:12217 Lewy body dementia
DOID:14330 Parkinson's disease

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026