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Guidelines

MIRAGE

PRELI domain containing 1

Summary

Gene Symbol

Prelid1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

66494

KEGG Gene ID

PubChem

66494

Alliance of Genome Resources

MGI:1913744

Annotation

Keyword

Apoptosis
Lipid transport
Mitochondrion
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8R107	Px19-like protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 31 in total

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GO Term	Evidence Code	PMID
apoptotic process
negative regulation of mitochondrial membrane potential	ISS
negative regulation of mitochondrial membrane potential	ISO
negative regulation of mitochondrial membrane potential	IEA
positive regulation of endopeptidase activity	ISS

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

regulation of membrane lipid distribution

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

phospholipid transport

organophosphate ester transport [inference]

phospholipid transport

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation

regulation of T cell activation [inference]

regulation of T cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

regulation of phospholipid transport [inference]

positive regulation of phospholipid transport

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

regulation of phospholipid transport [inference]

positive regulation of phospholipid transport

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

positive regulation of cellular respiration

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of phospholipid transport

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

positive regulation of cellular respiration

regulation of generation of precursor metabolites and energy [inference]

regulation of cellular respiration [inference]

positive regulation of cellular respiration

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of endopeptidase activity [inference]

positive regulation of endopeptidase activity

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of endopeptidase activity [inference]

positive regulation of endopeptidase activity

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process

negative regulation of apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of leukocyte apoptotic process [inference]

regulation of lymphocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process

regulation of T cell apoptotic process [inference]

positive regulation of T cell apoptotic process

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

positive regulation of cellular respiration

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation

regulation of T cell activation [inference]

regulation of T cell differentiation

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of mitochondrion organization [inference]

regulation of release of cytochrome c from mitochondria [inference]

negative regulation of release of cytochrome c from mitochondria

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of release of cytochrome c from mitochondria

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation

regulation of T cell activation [inference]

regulation of T cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation

regulation of biological quality [inference]

regulation of membrane potential [inference]

negative regulation of membrane potential [inference]

negative regulation of mitochondrial membrane potential

regulation of mitochondrial membrane potential

negative regulation of mitochondrial membrane potential

regulation of membrane lipid distribution

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of hydrolase activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity

regulation of endopeptidase activity [inference]

positive regulation of endopeptidase activity

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
mitochondrion	ISO
mitochondrion	IDA
mitochondrion	IEA
mitochondrial intermembrane space	ISS

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

nucleoplasm

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

organelle envelope lumen [inference]

mitochondrial intermembrane space

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
phosphatidic acid transfer activity	ISO
phosphatidic acid transfer activity	IBA
phosphatidic acid transfer activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

lipid transfer activity [inference]

phospholipid transfer activity [inference]

phosphatidic acid transfer activity

molecular carrier activity [inference]

lipid carrier activity [inference]

lipid transfer activity [inference]

phospholipid transfer activity [inference]

phosphatidic acid transfer activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

PRELI domain-containing protein 1, mitochondrial

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
phosphatidic acid transfer activity

Displaying **all 2** entries
InterPro
PRELI/MSF1 domain
Slowmo/Ups family

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026