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MIRAGE
leucine-rich repeat kinase 2
Summary
- Gene Symbol
-
- Lrrk2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Autophagy
- Cell projection
- Coiled coil
- Cytoplasmic vesicle
- Cytoskeleton
- Differentiation
- Endoplasmic reticulum
- Endosome
- GTP-binding
- GTPase activation
- Golgi apparatus
- Hydrolase
- Leucine-rich repeat
- Lysosome
- Mitochondrion outer membrane
- Phosphoprotein
- Reference proteome
- Repeat
- Serine/threonine-protein kinase
- Synapse
- Ubl conjugation
- WD repeat
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| MAPK cascade |
|
|
| MAPK cascade |
|
|
| protein phosphorylation |
|
|
| protein phosphorylation |
|
|
| protein phosphorylation |
|
GO Hierarchy
- regulation of locomotion
- regulation of reactive oxygen species metabolic process
- regulation of synaptic vesicle transport
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane |
|
|
| Golgi membrane |
|
|
| Golgi membrane |
|
|
| nucleoplasm |
|
|
| cytoplasm |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| SNARE binding |
|
|
| SNARE binding |
|
|
| magnesium ion binding |
|
|
| magnesium ion binding |
|
|
| actin binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Leucine-rich repeat serine/threonine-protein kinase
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| GTP binding |
| kinase activity |
| nucleotide binding |
| phosphorylation |
Rhea
