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solute carrier family 39 (metal ion transporter), member 8

Summary

Gene Symbol

Slc39a8

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

67547

KEGG Gene ID

[""]

PubChem

67547

Alliance of Genome Resources

MGI:1914797

Annotation

Keyword

Alternative splicing
Cell membrane
Glycoprotein
Lysosome
Reference proteome
Signal
Symport
Transmembrane helix
Zinc transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q91W10	Solute carrier family 39 member 8 Zrt- and Irt-like protein 8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 62 in total

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GO Term	Evidence Code	PMID
transcription, DNA-templated	IMP
DNA-templated transcription	IMP
regulation of DNA-templated transcription	ISO
regulation of transcription, DNA-templated	ISO
regulation of DNA-templated transcription	IMP

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte adhesion to arterial endothelial cell

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

transcription, DNA-templated

amino acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

arginine metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

arginine metabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

cadmium ion transmembrane transport

manganese ion transmembrane transport

mitochondrial manganese ion transmembrane transport

zinc ion transmembrane transport

zinc ion import across plasma membrane

plasma membrane selenite transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

cellular detoxification [inference]

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

cartilage homeostasis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

cartilage homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

manganese ion homeostasis [inference]

intracellular manganese ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

inorganic ion homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell [inference]

iron ion import across plasma membrane

intracellular zinc ion homeostasis

manganese ion homeostasis [inference]

intracellular manganese ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport

transition metal ion transport [inference]

cobalt ion transport

iron ion transport [inference]

iron import into cell [inference]

iron ion import across plasma membrane

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

manganese ion transport [inference]

manganese ion transmembrane transport

mitochondrial manganese ion transmembrane transport

zinc ion transport

zinc ion transmembrane transport

zinc ion import across plasma membrane

cadmium ion transport [inference]

cadmium ion transmembrane transport

mercury ion transport

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

cadmium ion transmembrane transport

manganese ion transmembrane transport

mitochondrial manganese ion transmembrane transport

zinc ion transmembrane transport

zinc ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

cadmium ion transmembrane transport

manganese ion transmembrane transport

mitochondrial manganese ion transmembrane transport

zinc ion transmembrane transport

zinc ion import across plasma membrane

organic anion transport [inference]

bicarbonate transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across plasma membrane

cadmium ion transmembrane transport

manganese ion transmembrane transport

mitochondrial manganese ion transmembrane transport

zinc ion transmembrane transport

zinc ion import across plasma membrane

plasma membrane selenite transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

establishment of localization in cell [inference]

iron import into cell [inference]

iron ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of biological quality [inference]

regulation of membrane potential

detoxification [inference]

detoxification of inorganic compound [inference]

detoxification of cadmium ion [inference]

cellular detoxification of cadmium ion

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

cellular detoxification [inference]

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
lysosomal membrane	ISS
lysosomal membrane	ISO
lysosomal membrane	IEA
plasma membrane	ISO
plasma membrane	IDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

plasma membrane region [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
zinc ion transmembrane transporter activity	IBA
metal ion transmembrane transporter activity	IEA
monoatomic cation:bicarbonate symporter activity	ISO
monoatomic cation:bicarbonate symporter activity	IDA
monoatomic cation:bicarbonate symporter activity	IBA