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signal transducer and activator of transcription 4

Summary

Gene Symbol

STAT4

Organism

Homo sapiens (human)

External Links

NCBI Gene

6775

PubChem

6775

Alliance of Genome Resources

HGNC:11365

Annotation

Keyword

Acetylation
Activator
Cytoplasm
DNA-binding
Disease variant
Nucleus
Phosphoprotein
Reference proteome
SH2 domain
Systemic lupus erythematosus
Transcription regulation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q14765

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
interleukin-12-mediated signaling pathway	IDA	7638186
regulation of cell population proliferation	IBA
response to peptide hormone	IBA
T-helper 1 cell differentiation	IDA	14688310
positive regulation of transcription by RNA polymerase II	NAS	15864272 24058793

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell activation [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell activation [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell activation [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell activation [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interleukin-12-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell activation [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell activation [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

response to stimulus [inference]

response to stress [inference]

defense response

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone

response to cytokine [inference]

response to interleukin-6

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interleukin-12-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
chromatin	ISA
nucleus	IDA	7638186
nucleus	IMP	37256972
nucleus	IBA
nucleoplasm	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

transcription regulator complex [inference]

RNA polymerase II transcription regulator complex

protein-DNA complex [inference]

chromatin

nuclear protein-containing complex [inference]

RNA polymerase II transcription regulator complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

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GO Term	Evidence Code	PMID
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
DNA-binding transcription factor activity	IDA	31562212
DNA-binding transcription factor activity	IMP	37256972

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

transcription regulator activity [inference]

DNA-binding transcription factor activity

DNA-binding transcription factor activity, RNA polymerase II-specific

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

signal transducer and activator of transcription 4

Functional Category

G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cytokine-mediated signaling pathway
receptor signaling pathway via JAK-STAT
regulation of cell population proliferation
response to peptide hormone

Displaying **all 5** entries
InterPro
STAT transcription factor, DNA-binding
STAT transcription factor, all-alpha domain
STAT transcription factor, coiled coil
STAT transcription factor, protein interaction
Transcription factor STAT

Disease

Disease Ontology

Displaying entries **11 - 18** of 18 in total

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DO ID	Disease Name	Source
DOID:2048	autoimmune hepatitis	Alliance of Genome Resources
DOID:2986	IgA glomerulonephritis	Alliance of Genome Resources
DOID:418	systemic scleroderma	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources
DOID:8704	genital herpes	Alliance of Genome Resources
DOID:8893	psoriasis	Alliance of Genome Resources
DOID:9008	psoriatic arthritis	Alliance of Genome Resources
DOID:9074	systemic lupus erythematosus	Alliance of Genome Resources

Ortholog

Displaying entries **81 - 89** of 89 in total

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Species	Gene ID	Orthologous MAtrix
Sparus aurata	115587839	SPAAU27819
Strigops habroptila	115608874	STRHB03296
Corvus moneduloides	116446452	CORMO24149
Chelonoidis abingdonii	116815205	CHEAB09954
Rhinolophus ferrumequinum	117025897	RHIFE13954
Scophthalmus maximus	118282786	SCOMX06339
Balaenoptera musculus	118898551	BALMU00532
Panthera leo	122226404	PANLE11257
Pongo abelii	129054459	PONAB23935

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements