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ATPase family, AAA domain containing 1

Summary

Gene Symbol

Atad1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

67979

KEGG Gene ID

[""]

PubChem

67979

Alliance of Genome Resources

MGI:1915229

Annotation

Keyword

3D-structure
ATP-binding
Cell membrane
Mitochondrion outer membrane
Peroxisome
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Translocase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9D5T0	ATPase family AAA domain-containing protein 1 Thorase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
positive regulation of receptor internalization	IMP
learning	IMP
memory	IMP
negative regulation of synaptic transmission, glutamatergic	IMP
regulation of postsynaptic neurotransmitter receptor internalization	IDA

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

establishment of protein localization to membrane [inference]

extraction of mislocalized protein from membrane [inference]

extraction of mislocalized protein from mitochondrial outer membrane

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

behavior [inference]

learning or memory [inference]

localization [inference]

establishment of localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

extraction of mislocalized protein from membrane [inference]

extraction of mislocalized protein from mitochondrial outer membrane

cellular localization [inference]

localization within membrane [inference]

establishment of protein localization to membrane [inference]

extraction of mislocalized protein from membrane [inference]

extraction of mislocalized protein from mitochondrial outer membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of synaptic transmission, glutamatergic [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of cellular process [inference]

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of synaptic transmission, glutamatergic [inference]

negative regulation of synaptic transmission, glutamatergic

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of biological quality [inference]

regulation of postsynaptic neurotransmitter receptor internalization

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
mitochondrion	HDA
mitochondrial outer membrane	ISS
mitochondrial outer membrane	ISO
mitochondrial outer membrane	IBA
mitochondrial outer membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

organelle outer membrane [inference]

mitochondrial outer membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

postsynapse

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
ATP binding	IEA
ATP hydrolysis activity	IDA
ATP hydrolysis activity	IEA
membrane protein dislocase activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular carrier activity [inference]

protein carrier activity [inference]

membrane protein dislocase activity

ATP-dependent activity [inference]

membrane protein dislocase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATPase

Functional Category

L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ATP binding
extraction of mislocalized protein from mitochondrial outer membrane
nucleotide binding

Displaying **all 5** entries
InterPro
AAA ATPase, AAA+ lid domain
AAA+ ATPase domain
ATPase, AAA-type, conserved site
ATPase, AAA-type, core
P-loop containing nucleoside triphosphate hydrolase