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RAB14, member RAS oncogene family

Summary

Gene Symbol

Rab14

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

68365

KEGG Gene ID

PubChem

68365

Alliance of Genome Resources

MGI:1915615

Annotation

Keyword

Acetylation
Cytoplasmic vesicle
Direct protein sequencing
Endosome
GTP-binding
Golgi apparatus
Hydrolase
Magnesium
Membrane
Metal-binding
Methylation
Prenylation
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q50HX4
Q91V41

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
phagolysosome assembly	IBA
intracellular protein transport	IBA
Golgi to endosome transport	IMP
Golgi to endosome transport	IBA
Golgi to endosome transport	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

intercellular transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

vesicle-mediated transport [inference]

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

Golgi to endosome transport

early endosome to Golgi transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

localization within membrane [inference]

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization [inference]

phagolysosome assembly

vesicle organization [inference]

phagolysosome assembly

vesicle fusion [inference]

endosomal vesicle fusion

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

organelle assembly [inference]

phagolysosome assembly

phagosome maturation

cellular component assembly [inference]

organelle assembly [inference]

phagolysosome assembly

membrane organization [inference]

membrane fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport

intracellular protein transport

apical protein localization

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

protein transport

intracellular protein transport

vesicle-mediated transport [inference]

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

Golgi to endosome transport

early endosome to Golgi transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

secretion [inference]

body fluid secretion

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

establishment of protein localization [inference]

protein transport

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

localization within membrane [inference]

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion

Displaying entries **1 - 5** of 33 in total

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GO Term	Evidence Code	PMID
Golgi membrane	ISS
Golgi membrane	ISO
Golgi membrane	IEA
lysosome	ISO
early endosome	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

endosome membrane [inference]

early endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

endosome membrane [inference]

early endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

nuclear outer membrane-endoplasmic reticulum membrane network

plasma membrane region [inference]

apical plasma membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

secretory granule [inference]

lamellar body [inference]

alveolar lamellar body

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum [inference]

rough endoplasmic reticulum

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

secretory granule [inference]

lamellar body [inference]

alveolar lamellar body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum [inference]

rough endoplasmic reticulum

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

secretory granule [inference]

lamellar body [inference]

alveolar lamellar body

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
GTPase activity	ISS
GTPase activity	ISO
GTPase activity	TAS
GTPase activity	IBA
GTPase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

G protein activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

myosin binding [inference]

myosin V binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

GDP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

molecular function regulator activity [inference]

G protein activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

RAB

Functional Category

T: Signal transduction mechanisms
U: Intracellular trafficking, secretion, and vesicular transport

Displaying 1 entry
Gene Ontology
GTP binding

Displaying **all 3** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Small GTP-binding protein domain
Small GTPase

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	51552	HGNC:16524

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements