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Guidelines

MIRAGE

STEAP family member 3

Summary

Gene Symbol

Steap3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

68428

KEGG Gene ID

[""]

PubChem

68428

Alliance of Genome Resources

MGI:1915678

Annotation

Keyword

Alternative splicing
Apoptosis
Cell cycle
Copper
Endosome
FAD
Glycoprotein
Heme
Iron transport
NADP
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q8CI59	Dudulin-2 Protein nm1054 Six-transmembrane epithelial antigen of prostate 3 Tumor suppressor-activated pathway protein 6
E9QN92
A0A0R4J1G9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

1

2

3

4

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Last »
GO Term	Evidence Code	PMID
iron ion transport	IMP
apoptotic process
protein secretion	ISS
protein secretion	ISO
copper ion import	IDA

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

vesicle-mediated transport [inference]

exocytosis [inference]

exosomal secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport

iron ion import across cell outer membrane

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

exosomal secretion

protein secretion

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

inorganic ion homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

protein secretion

protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

copper ion transport [inference]

copper ion import

iron ion transport

iron import into cell

iron ion transmembrane transport

iron ion import across cell outer membrane

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport

iron ion import across cell outer membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport

iron ion import across cell outer membrane

protein transport [inference]

protein secretion

vesicle-mediated transport [inference]

exocytosis [inference]

exosomal secretion

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

exosomal secretion

protein secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport

iron ion import across cell outer membrane

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

exosomal secretion

protein secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization in cell [inference]

iron import into cell

establishment of vesicle localization [inference]

exosomal secretion

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

exosomal secretion

organelle localization [inference]

vesicle localization [inference]

establishment of vesicle localization [inference]

exosomal secretion

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

exosomal secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cellular response to stress [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
endosome	IDA
endosome	IBA
endosome	IEA
multivesicular body	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

late endosome [inference]

multivesicular body

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

late endosome [inference]

multivesicular body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

late endosome [inference]

multivesicular body

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
ferric-chelate reductase activity	IDA
ferric-chelate reductase activity	IMP
protein binding	IPI
cupric reductase (NADH) activity	IDA
cupric reductase (NADH) activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on metal ions [inference]

ferric-chelate reductase activity

ferric-chelate reductase (NADPH) activity

oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor [inference]

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

tetrapyrrole binding [inference]

heme binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Metalloreductase STEAP4

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
copper ion import
cupric reductase activity
ferric-chelate reductase (NADPH) activity

Displaying **all 3** entries
InterPro
Ferric reductase transmembrane component-like domain
NAD(P)-binding domain superfamily
Pyrroline-5-carboxylate reductase, catalytic, N-terminal

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026