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GPI-anchored HDL-binding protein 1

Summary

Gene Symbol

Gpihbp1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

68453

KEGG Gene ID

PubChem

68453

Alliance of Genome Resources

MGI:1915703

Annotation

Keyword

Cell membrane
Disulfide bond
GPI-anchor
Hyperlipidemia
Lipid-binding
Reference proteome
Signal
Sulfation
Transport

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q9D1N2	High density lipoprotein-binding protein 1
A0A087WPI6
A0A087WNV7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
lipid transport	IDA
intracellular protein transport	IDA
positive regulation of very-low-density lipoprotein particle remodeling	IDA
protein import	IDA
triglyceride catabolic process	ISO

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

lipid catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride catabolic process

acylglycerol catabolic process [inference]

triglyceride catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

lipid catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride catabolic process

acylglycerol catabolic process [inference]

triglyceride catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

vesicle-mediated transport [inference]

transcytosis

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

multicellular organismal process [inference]

transcytosis

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

acylglycerol homeostasis [inference]

triglyceride homeostasis

sterol homeostasis [inference]

cholesterol homeostasis

response to stimulus [inference]

response to chemical [inference]

response to nitrogen compound [inference]

response to heparin

response to oxygen-containing compound [inference]

response to heparin

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

protein localization to cell surface

establishment of localization [inference]

transport [inference]

lipid transport

protein transport [inference]

vesicle-mediated transport [inference]

transcytosis

intracellular transport [inference]

intracellular protein transport

establishment of protein localization [inference]

protein transport [inference]

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport

positive regulation of transport [inference]

positive regulation of lipid transport

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport

positive regulation of lipid localization [inference]

positive regulation of lipid transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular component organization [inference]

positive regulation of transport [inference]

positive regulation of lipid transport

positive regulation of multicellular organismal process [inference]

positive regulation of very-low-density lipoprotein particle remodeling

positive regulation of lipoprotein particle clearance [inference]

positive regulation of chylomicron remnant clearance

positive regulation of chylomicron remodeling

positive regulation of lipid localization [inference]

positive regulation of lipid transport

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of small molecule metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular component organization [inference]

regulation of cellular component organization [inference]

regulation of very-low-density lipoprotein particle remodeling [inference]

positive regulation of very-low-density lipoprotein particle remodeling

positive regulation of cellular component organization [inference]

regulation of chylomicron remodeling [inference]

positive regulation of chylomicron remodeling

regulation of multicellular organismal process [inference]

regulation of very-low-density lipoprotein particle remodeling [inference]

positive regulation of very-low-density lipoprotein particle remodeling

regulation of lipoprotein particle clearance [inference]

positive regulation of lipoprotein particle clearance [inference]

positive regulation of chylomicron remnant clearance

regulation of chylomicron remnant clearance [inference]

positive regulation of chylomicron remnant clearance

positive regulation of multicellular organismal process [inference]

positive regulation of very-low-density lipoprotein particle remodeling

positive regulation of lipoprotein particle clearance [inference]

positive regulation of chylomicron remnant clearance

positive regulation of chylomicron remodeling

regulation of chylomicron remodeling [inference]

positive regulation of chylomicron remodeling

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	EXP
plasma membrane	IDA
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

plasma membrane region [inference]

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
high-density lipoprotein particle binding	IDA
lipid binding
lipase binding	ISO
lipase binding	IBA
lipase binding	IPI

GO Hierarchy

molecular function

transporter activity [inference]

protein transporter activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

lipase binding

lipid binding

protein-containing complex binding [inference]

protein-lipid complex binding [inference]

lipoprotein particle binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

lipase activator activity [inference]

lipoprotein lipase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

lipase activator activity [inference]

lipoprotein lipase activator activity

molecular carrier activity [inference]

protein carrier activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
chylomicron binding
lipase binding
triglyceride homeostasis

Displaying **all 2** entries
InterPro
Ly-6 antigen/uPA receptor-like
Snake toxin-like superfamily

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	338328	HGNC:24945

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements