Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
spleen associated tyrosine kinase
Summary
- Gene Symbol
-
- SYK
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Adaptive immunity
- Alternative splicing
- Angiogenesis
- Cell membrane
- Cytoplasm
- Disease variant
- Host-virus interaction
- Innate immunity
- Kinase
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- SH2 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis |
|
|
| cell activation |
|
|
| cell activation |
|
|
| lymph vessel development |
|
|
| lymph vessel development |
|
GO Hierarchy
- apoptotic signaling pathway
- regulation of neutrophil degranulation
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of bone resorption
- positive regulation of cold-induced thermogenesis
- regulation of neutrophil degranulation
- apoptotic signaling pathway
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of type I interferon production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-3 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of bone resorption
- positive regulation of cold-induced thermogenesis
biological process
immune system process [inference]
cellular process [inference]
cell activation
signal transduction [inference]
immune response-regulating signaling pathway [inference]
cell surface receptor signaling pathway [inference]
metabolic process [inference]
multicellular organismal process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
positive regulation of leukocyte activation [inference]
positive regulation of immune response [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of immune effector process [inference]
regulation of immune response
immune response-regulating signaling pathway [inference]
regulation of innate immune response [inference]
positive regulation of immune response [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of leukocyte activation [inference]
positive regulation of immune response [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of cell communication [inference]
positive regulation of cell adhesion [inference]
positive regulation of cell activation [inference]
positive regulation of response to stimulus [inference]
positive regulation of response to biotic stimulus [inference]
positive regulation of signal transduction [inference]
positive regulation of defense response [inference]
positive regulation of response to external stimulus [inference]
positive regulation of immune response [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
positive regulation of cell activation [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
positive regulation of response to biotic stimulus [inference]
positive regulation of signal transduction [inference]
positive regulation of defense response [inference]
positive regulation of response to external stimulus [inference]
positive regulation of immune response [inference]
regulation of immune response
immune response-regulating signaling pathway [inference]
regulation of innate immune response [inference]
positive regulation of immune response [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
immune response-regulating signaling pathway [inference]
cell surface receptor signaling pathway [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of cell adhesion [inference]
regulation of cell-cell adhesion [inference]
positive regulation of cell adhesion [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of cell communication [inference]
positive regulation of cell adhesion [inference]
positive regulation of cell activation [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
positive regulation of cell activation [inference]
regulation of vesicle-mediated transport [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
positive regulation of cell activation [inference]
regulation of multicellular organismal development [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphotyrosine residue binding |
|
|
| protein kinase activity |
|
|
| protein kinase activity |
|
|
| protein kinase activity |
|
|
| protein serine/threonine kinase activity |
|
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- protein kinase
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| kinase activity |
| non-membrane spanning protein tyrosine kinase activity |
| nucleotide binding |
| phosphorylation |
| transferase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:612 | primary immunodeficiency disease |
