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MIRAGE
TATA-box binding protein
Summary
- Gene Symbol
-
- TBP
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- DNA-binding
- Disease variant
- Host-virus interaction
- Nucleus
- Reference proteome
- Repeat
- Spinocerebellar ataxia
- Transcription
- Transcription regulation
- Triplet repeat expansion
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase I preinitiation complex assembly | ||
| DNA-templated transcription initiation | ||
| transcription by RNA polymerase II | ||
| transcription by RNA polymerase II | ||
| transcription by RNA polymerase II |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
biosynthetic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| transcription factor TFIIA complex | ||
| cytoplasm |
|
|
| cytosol | ||
| protein-containing complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| transcription cis-regulatory region binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| RNA polymerase II core promoter sequence-specific DNA binding | ||
| RNA polymerase III general transcription initiation factor activity | ||
| core promoter sequence-specific DNA binding |
GO Hierarchy
molecular function
binding [inference]
organic cyclic compound binding [inference]
nucleic acid binding [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- TBP
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| InterPro |
|---|
| TATA-box binding protein, conserved site |
| TATA-box binding protein, eukaryotic |
| TATA-box binding protein |
| TBP domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050967 | spinocerebellar ataxia type 17 | |
| DOID:0060892 | late onset Parkinson's disease | |
| DOID:5419 | schizophrenia | |
| DOID:9744 | type 1 diabetes mellitus |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6908 | Xenbase:XB-GENE-488470 | ||
| 21374 | MOUSE21736 | ||
| 117526 | RATNO17172 | ||
| 368882 | DANRE05845 | ||
| 446042 | TAKRU34739 | ||
| 516578 | BOVIN36161 | ||
| 611193 | CANLF03095 | ||
| 696258 | MACMU33989 | ||
| 738472 | PANTR39552 | ||
| 100028736 | MONDO11619 |
