GlyCosmos Portal

Submissions

3-ketodihydrosphingosine reductase

Summary

Gene Symbol

KDSR

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 700476
KEGG Gene ID: mcc:700476
PubChem: 700476

Annotation

Keyword

Endoplasmic reticulum
NADP
Oxidoreductase
Reference proteome
Signal
Sphingolipid metabolism

Proteins

Displaying 1 entry
UniProt	Protein Name
F7HPT5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
3-keto-sphinganine metabolic process	IEA	22301074 30032202
sphingolipid biosynthetic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid metabolic process [inference]

3-keto-sphinganine metabolic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

3-keto-sphinganine metabolic process

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid metabolic process [inference]

3-keto-sphinganine metabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid metabolic process [inference]

3-keto-sphinganine metabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

small molecule metabolic process [inference]

cellular ketone metabolic process [inference]

3-keto-sphinganine metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid metabolic process [inference]

3-keto-sphinganine metabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular ketone metabolic process [inference]

3-keto-sphinganine metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid metabolic process [inference]

3-keto-sphinganine metabolic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

3-keto-sphinganine metabolic process

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid metabolic process [inference]

3-keto-sphinganine metabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
3-dehydrosphinganine reductase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

3-dehydrosphinganine reductase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dehydrogenase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
oxidoreductase activity

Displaying **all 2** entries
InterPro
NAD(P)-binding domain superfamily
Short-chain dehydrogenase/reductase SDR

KEGG BRITE Database

Orthology

K04708

Name

3-dehydrosphinganine reductase [EC:1.1.1.102]

References

15328338

Rhea

RHEA:22640

sphinganine + NADP⁺

H⁺ + NADPH + 3-oxosphinganine

Enzyme

1.1.1.102

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP014285
Gene Name: 3-ketodihydrosphingosine reductase

Ortholog

Displaying entries **71 - 74** of 74 in total

« First

‹ Prev

…

4

5

6

7

8
Species	Gene ID	Orthologous MAtrix
Balaenoptera musculus	118906962	BALMU02847
Cyprinus carpio carpio	122136174	CYPCA40427
Panthera leo	122203368	PANLE00553
Ursus americanus	123787454	URSAM11749

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements