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integrator complex subunit 2

Summary

Gene Symbol

Ints2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

70422

KEGG Gene ID

PubChem

70422

Annotation

Keyword

Alternative splicing
Cytoplasm
Nucleus
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A1S6GWJ5
Q3TPV8
Q80UK8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
snRNA processing	ISS
snRNA processing	ISO
snRNA processing	IEA
regulation of transcription elongation by RNA polymerase II	ISO
snRNA 3'-end processing	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance [inference]

nuclear RNA surveillance [inference]

RNA polymerase II transcription initiation surveillance

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance [inference]

nuclear RNA surveillance [inference]

RNA polymerase II transcription initiation surveillance

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance [inference]

nuclear RNA surveillance [inference]

RNA polymerase II transcription initiation surveillance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

RNA surveillance [inference]

nuclear RNA surveillance [inference]

RNA polymerase II transcription initiation surveillance

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance [inference]

nuclear RNA surveillance [inference]

RNA polymerase II transcription initiation surveillance

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance [inference]

nuclear RNA surveillance [inference]

RNA polymerase II transcription initiation surveillance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

RNA surveillance [inference]

nuclear RNA surveillance [inference]

RNA polymerase II transcription initiation surveillance

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance [inference]

nuclear RNA surveillance [inference]

RNA polymerase II transcription initiation surveillance

RNA processing [inference]

snRNA processing

snRNA 3'-end processing

RNA 3'-end processing [inference]

snRNA 3'-end processing

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

Displaying entries **1 - 5** of 15 in total

1

2

3

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	ISO
nucleus	IEA
cytoplasm	ISS
cytoplasm	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

organelle membrane [inference]

nuclear membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying 1 entry
GO Term	Evidence Code	PMID
molecular_function	ND

GO Hierarchy

molecular function

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Integrator complex subunit 2

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
snRNA 3'-end processing
snRNA processing

Displaying **all 2** entries
InterPro
Integrator complex subunit 2, metazoa
Integrator complex subunit 2

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Last updated: April 6, 2026

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Acknowledgements