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MIRAGE
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

Summary
Gene Symbol
  • ST8SIA1
Organism
Macaca mulatta (Rhesus monkey)
NCBI Gene
706707
KEGG Gene ID
mcc:706707
PubChem
706707
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Sphingolipid metabolism
  • Transferase
  • Transmembrane helix
Proteins
Displaying all 3 entries
UniProt Protein Name
G7N6I4
  • Alpha-2,8-sialyltransferase 8A
  • Ganglioside GD3 synthase
  • Sialyltransferase 8A
  • Sialyltransferase St8Sia I
A0A8J8XLB9
  • Alpha-2,8-sialyltransferase 8A
  • Ganglioside GD3 synthase
  • Sialyltransferase 8A
  • Sialyltransferase St8Sia I
F6Z009
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 3 entries
GO Term Evidence Code PMID
protein glycosylation
N-glycan processing
oligosaccharide metabolic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
KEGG BRITE Database
Orthology
K03371
Name
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.3.8]
References
Reactions
Displaying all 4 entries
KEGG Reaction Enzyme Acceptor Product
R13175
R05947
R05940
R06032
Rhea

RHEA:19313

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP014921
Gene Name
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Ortholog
Displaying entries 1 - 10 of 75 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
6489 HUMAN11629
20449 MOUSE47956
25280 RATNO31134
282352 BOVIN30100
465341 PANTR06305
477672 CANLF10982
553210 DANRE33846
100011205 MONDO35153
100080234 ORNAN14742
100174872 GASAC21600
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025